Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.
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Human telomerase and its regulationIdentification of PITX1 as a TERT suppressor gene located on human chromosome 5CTCF binds the proximal exonic region of hTERT and inhibits its transcription.The proximal promoter region of mTert is sufficient to regulate telomerase activity in ES cells and transgenic animalsTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneSp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cellsVariation at the TERT locus and predisposition for cancerRole of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFbetaNatural and pharmacological regulation of telomerasePurification and identification of a transcription factor, USF-2, binding to E-box element in the promoter of human telomerase reverse transcriptase (hTERT).Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repressionTelomeres and immunological diseases of agingEpigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells.Regulation of the human catalytic subunit of telomerase (hTERT).Regulation of the human telomerase reverse transcriptase gene.Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology.Demethylation of the hTERT promoter in normal human gastric mucosal epithelial cells following N-methyl-N'-nitro-N-nitrosoguanidine exposure.A Combinatory Strategy for Detection of Live CTCs Using Microfiltration and a New Telomerase-Selective AdenovirusThe importance of the telomere and telomerase system in hematological malignancies.Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cellsHepatitis B virus X gene induces human telomerase reverse transcriptase mRNA expression in cultured normal human cholangiocytes.Telomerase as a useful target in cancer fighting-the breast cancer case.An unbiased in vivo screen reveals multiple transcription factors that control HPV E6-regulated hTERT in keratinocytes.Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene.Human telomerase expression regulation.Telomerase regulation.Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3.Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.Repression of telomerase gene promoter requires human-specific genomic context and is mediated by multiple HDAC1-containing corepressor complexes.Telomerase Induction in HPV Infection and Oncogenesis.Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells.The hTERT and hTERC telomerase gene promoters are activated by the second exon of the adenoviral protein, E1A, identifying the transcriptional corepressor CtBP as a potential repressor of both genes.Regulation of myeloid zinc finger protein 2A transactivation activity through phosphorylation by mitogen-activated protein kinases.Human papillomavirus E2 down-regulates the human telomerase reverse transcriptase promoter.Transcriptional regulation of Kaposi's sarcoma-associated herpesvirus-encoded oncogene viral interferon regulatory factor by a novel transcriptional silencer, Tis.The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus transactivates the telomerase reverse transcriptase promoter.NFX1-123 increases hTERT expression and telomerase activity posttranscriptionally in human papillomavirus type 16 E6 keratinocytes.Transcriptional activation of hTERT, the human telomerase reverse transcriptase, by nuclear factor of activated T cells.The regulation of telomerase in oncogenesis.
P2860
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P2860
Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Identification and characteriz ...... riptional repression of hTERT.
@en
Identification and characteriz ...... n telomerase catalytic subunit
@nl
type
label
Identification and characteriz ...... riptional repression of hTERT.
@en
Identification and characteriz ...... n telomerase catalytic subunit
@nl
prefLabel
Identification and characteriz ...... riptional repression of hTERT.
@en
Identification and characteriz ...... n telomerase catalytic subunit
@nl
P2093
P2860
P356
P1476
Identification and characteriz ...... riptional repression of hTERT.
@en
P2093
K Fujimoto
M Takahashi
M Takakura
Y Kitagawa
P2860
P304
P356
10.1093/NAR/28.13.2557
P407
P577
2000-07-01T00:00:00Z