Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer.
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Atomic force microscopy: a multifaceted tool to study membrane proteins and their interactions with ligands.PDGF suppresses the sulfation of CD44v and potentiates CD44v-mediated binding of colon carcinoma cells to fibrin under flow.AFM force spectroscopy reveals how subtle structural differences affect the interaction strength between Candida albicans and DC-SIGN.The physics of cancer: the role of physical interactions and mechanical forces in metastasis.A hot-spot motif characterizes the interface between a designed ankyrin-repeat protein and its target ligand.Fibrin serves as a divalent ligand that regulates neutrophil-mediated melanoma cells adhesion to endothelium under shear conditionsDistinct kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen)Analytical cell adhesion chromatography reveals impaired persistence of metastatic cell rolling adhesion to P-selectin.Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow.β-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths.Glycomechanics of the metastatic cascade: tumor cell-endothelial cell interactions in the circulation.Receptors and ligands role in colon physiology and pathology.Holothurian glycosaminoglycan inhibits metastasis via inhibition of P-selectin in B16F10 melanoma cells.Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins.N-glycan mediated adhesion strengthening during pathogen-receptor binding revealed by cell-cell force spectroscopy.Characterization of monobody scaffold interactions with ligand via force spectroscopy and steered molecular dynamics.Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways.Microtubules tune mechanotransduction through NOX2 and TRPV4 to decrease sclerostin abundance in osteocytes.P-, but not E- or L-, selectin-mediated rolling adhesion persistence in hemodynamic flow diverges between metastatic and leukocytic cells.E-selectin-mediated rolling facilitates pancreatic cancer cell adhesion to hyaluronic acid.
P2860
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P2860
Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Single-molecule binding of CD4 ...... endent interactions in cancer.
@en
Single-molecule binding of CD4 ...... endent interactions in cancer.
@nl
type
label
Single-molecule binding of CD4 ...... endent interactions in cancer.
@en
Single-molecule binding of CD4 ...... endent interactions in cancer.
@nl
prefLabel
Single-molecule binding of CD4 ...... endent interactions in cancer.
@en
Single-molecule binding of CD4 ...... endent interactions in cancer.
@nl
P2093
P2860
P356
P1476
Single-molecule binding of CD4 ...... endent interactions in cancer.
@en
P2093
Christina S Alves
Denis Wirtz
Konstantinos Konstantopoulos
Phrabha S Raman
P2860
P304
P356
10.1242/JCS.079814
P407
P577
2011-05-10T00:00:00Z