Alternative splicing of SYK regulates mitosis and cell survival. - Wikidata - wikimedia - TriplyDB

Alternative splicing of SYK regulates mitosis and cell survival.

Alternative splicing of SYK regulates mitosis and cell survival.

http://www.wikidata.org/entity/Q39546323

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Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators Misregulation of pre-mRNA alternative splicing in cancer Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs jSplice: a high-performance method for accurate prediction of alternative splicing events and its application to large-scale renal cancer transcriptome data.Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.Getting Syk: spleen tyrosine kinase as a therapeutic target.Syk interacts with and phosphorylates nucleolin to stabilize Bcl-x(L) mRNA and promote cell survival.Diversity in TAF proteomics: consequences for cellular differentiation and migration.Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer.Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration.Tumor microenvironment-associated modifications of alternative splicing.Alternative splicing in oncogenic kinases: from physiological functions to cancer Splicing programs and cancer Identification of mRNA isoform switching in breast cancer.Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq.Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy.Identification of novel splice variants and exons of human endothelial cell-specific chemotaxic regulator (ECSCR) by bioinformatics analysis.RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia.CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma.ER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy.The prognostic potential of alternative transcript isoforms across human tumors.Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression.Genome-wide analysis of alternative splicing during human heart development.Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia.Expression of variant isoforms of the tyrosine kinase SYK determines the prognosis of hepatocellular carcinoma.Redirecting splicing with bifunctional oligonucleotides.My road to alternative splicing control: from simple paths to loops and interconnections.Novel splice-switching oligonucleotide promotes BRCA1 aberrant splicing and susceptibility to PARP inhibitor action.Full-length spleen tyrosine kinase inhibits the invasion and metastasis of human laryngeal squamous cell carcinoma Differential expression and alternative splicing of cell cycle genes in imatinib-treated K562 cells.Systems-level analysis of clinically different phenotypes of juvenile nasopharyngeal angiofibromas.Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes.Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication.High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.Alternative Splicing as a Target for Cancer Treatment.Suppression of Spleen Tyrosine Kinase (Syk) by Histone Deacetylation Promotes, Whereas BAY61-3606, a Synthetic Syk Inhibitor Abrogates Colonocyte Apoptosis by ERK Activation.Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway.SYK inhibition blocks proliferation and migration of glioma cells and modifies the tumor microenvironment.

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Alternative splicing of SYK regulates mitosis and cell survival.

http://www.wikidata.org/entity/Q39546323

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Alternative splicing of SYK regulates mitosis and cell survival.

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Alternative splicing of SYK regulates mitosis and cell survival.

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type

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Alternative splicing of SYK regulates mitosis and cell survival.

@en

Alternative splicing of SYK regulates mitosis and cell survival.

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prefLabel

Alternative splicing of SYK regulates mitosis and cell survival.

@en

Alternative splicing of SYK regulates mitosis and cell survival.

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Nature Structural & Molecular Biology

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Alternative splicing of SYK regulates mitosis and cell survival.

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Benoit Chabot

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Daniel Garneau

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Daniel Gendron

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Elvy Lapointe

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Hanad Nwilati

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Jean-François Lucier

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Jean-Philippe Brosseau

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Jean-Pierre Perreault

http://www.w3.org/2001/XMLSchema#string

Julien Gervais-Bird

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Karine Tremblay

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scholarly article

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10.1038/NSMB.2040

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6

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18

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2011-05-08T00:00:00Z

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51107545

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1013924498

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21552259

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