Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.
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Role of microglia in central nervous system infectionsNeuroinflammation in Alzheimer's disease: chemokines produced by astrocytes and chemokine receptorsHIV-1 associated dementia: symptoms and causesBioinformatic analysis of HIV-1 entry and pathogenesis.HIV-1 induces cytoskeletal alterations and Rac1 activation during monocyte-blood-brain barrier interactions: modulatory role of CCR5Mode of coreceptor use by R5 HIV type 1 correlates with disease stage: a study of paired plasma and cerebrospinal fluid isolates.Genes contributing to prion pathogenesisInteraction with CD4 and antibodies to CD4-induced epitopes of the envelope gp120 from a microglial cell-adapted human immunodeficiency virus type 1 isolateDeterminants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domainsHIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications.Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.Genetic variation and HIV-associated neurologic disease.Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity.Human Mast cell progenitors can be infected by macrophagetropic human immunodeficiency virus type 1 and retain virus with maturation in vitro.Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system.Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate.Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transportCryptococcus neoformans induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta in human microglia: role of specific antibody and soluble capsular polysaccharide.M-tropic HIV envelope protein gp120 exhibits a different neuropathological profile than T-tropic gp120 in rat striatumSingle genome analysis reveals genetic characteristics of Neuroadaptation across HIV-1 envelope.Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion.The role of gap junction channels during physiologic and pathologic conditions of the human central nervous systemAntiretroviral therapy in macrophages: implication for HIV eradication.A human immunodeficiency virus type 1 isolate from an infected person homozygous for CCR5Delta32 exhibits dual tropism by infecting macrophages and MT2 cells via CXCR4.Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.CNS-specific expression of C3a and C5a exacerbate demyelination severity in the cuprizone model.TCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infectionA machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia.Lentiviral neuropathogenesis: comparative neuroinvasion, neurotropism, neurovirulence, and host neurosusceptibilityNeurotrophins modulate the expression of chemokine receptors in the brain.Identification of a subset of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus strains able to exploit an alternative coreceptor on untransformed human brain and lymphoid cells.HIV-1 Tat activates a RhoA signaling pathway to reduce NMDA-evoked calcium responses in hippocampal neurons via an actin-dependent mechanismThe HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.Neuroimmunity and the blood-brain barrier: molecular regulation of leukocyte transmigration and viral entry into the nervous system with a focus on neuroAIDS.HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activityNovel mechanisms of central nervous system damage in HIV infection.Human retinal microglia express candidate receptors for HIV-1 infection.Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development.Neuropathogenesis of lentiviral infection in macaques: roles of CXCR4 and CCR5 viruses and interleukin-4 in enhancing monocyte chemoattractant protein-1 production in macrophages.When human immunodeficiency virus meets chemokines and microglia: neuroprotection or neurodegeneration?
P2860
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P2860
Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Microglia express CCR5, CXCR4, ...... irus type 1 dementia isolates.
@en
Microglia express CCR5, CXCR4, ...... irus type 1 dementia isolates.
@nl
type
label
Microglia express CCR5, CXCR4, ...... irus type 1 dementia isolates.
@en
Microglia express CCR5, CXCR4, ...... irus type 1 dementia isolates.
@nl
prefLabel
Microglia express CCR5, CXCR4, ...... irus type 1 dementia isolates.
@en
Microglia express CCR5, CXCR4, ...... irus type 1 dementia isolates.
@nl
P2093
P2860
P1433
P1476
Microglia express CCR5, CXCR4, ...... virus type 1 dementia isolates
@en
P2093
A V Albright
D Pleasure
F González-Scarano
M J O'Connor
P2860
P304
P407
P577
1999-01-01T00:00:00Z