Decreased accumulation or increased isoleucyl-tRNA synthetase activity confers resistance to the cyclic beta-amino acid BAY 10-8888 in Candida albicans and Candida tropicalis.
about
Dispersed disease-causing neomorphic mutations on a single protein promote the same localized conformational opening.Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin.Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans.Amino Acid Metabolism and Transport Mechanisms as Potential Antifungal Targets.
P2860
Decreased accumulation or increased isoleucyl-tRNA synthetase activity confers resistance to the cyclic beta-amino acid BAY 10-8888 in Candida albicans and Candida tropicalis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Decreased accumulation or incr ...... bicans and Candida tropicalis.
@en
Decreased accumulation or incr ...... bicans and Candida tropicalis.
@nl
type
label
Decreased accumulation or incr ...... bicans and Candida tropicalis.
@en
Decreased accumulation or incr ...... bicans and Candida tropicalis.
@nl
prefLabel
Decreased accumulation or incr ...... bicans and Candida tropicalis.
@en
Decreased accumulation or incr ...... bicans and Candida tropicalis.
@nl
P2860
P1476
Decreased accumulation or incr ...... bicans and Candida tropicalis.
@en
P2093
Ziegelbauer K
P2860
P304
P407
P577
1998-07-01T00:00:00Z