LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s).
about
Nuclear receptors in bone physiology and diseasesInhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon ReceptorLRP5 and LRP6 in development and diseaseDissecting molecular differences between Wnt coreceptors LRP5 and LRP6RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix.p53 and microRNA-34 are suppressors of canonical Wnt signaling.Modulation of β-catenin signaling by glucagon receptor activation.Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.Cyclooxygenase-2 suppresses the anabolic response to PTH infusion in mice.LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling.Update on Wnt signaling in bone cell biology and bone disease.Lipoprotein receptor-related protein 6 is required for parathyroid hormone-induced Sost suppression.Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme.Frizzled and LRP5/6 receptors for Wnt/β-catenin signalingPTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling.Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH.Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice.Function of matrix IGF-1 in coupling bone resorption and formation.G protein trafficking.N-cadherin restrains PTH repressive effects on sclerostin/SOST by regulating LRP6-PTH1R interaction.The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.Receptor tyrosine kinases: molecular switches regulating CNS axon regeneration.N-cadherin restrains PTH activation of Lrp6/β-catenin signaling and osteoanabolic action.The curious case of Gαs gain-of-function in neoplasia.Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing
P2860
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P2860
LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s).
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
LRP6 mediates cAMP generation ...... g the membrane targeting of Gα
@nl
LRP6 mediates cAMP generation ...... e membrane targeting of Gα(s).
@en
type
label
LRP6 mediates cAMP generation ...... g the membrane targeting of Gα
@nl
LRP6 mediates cAMP generation ...... e membrane targeting of Gα(s).
@en
prefLabel
LRP6 mediates cAMP generation ...... g the membrane targeting of Gα
@nl
LRP6 mediates cAMP generation ...... e membrane targeting of Gα(s).
@en
P2093
P2860
P1433
P1476
LRP6 mediates cAMP generation ...... e membrane targeting of Gα(s).
@en
P2093
Bart O Williams
Charlotta Lindvall
Fengjie Zhang
Hairong Ma
Katie Herbst
P2860
P356
10.1126/SCISIGNAL.2001464
P577
2011-03-15T00:00:00Z