PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
about
PDK1 regulates B cell differentiation and homeostasis.PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsivenessDichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency.The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning.Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.Assembly and Function of the Precursor B-Cell Receptor.Next-generation sequencing of a family with a high penetrance of monoclonal gammopathies for the identification of candidate risk alleles.The PI3K pathway in B cell metabolismRegulation mechanism of PDK1 on macrophage metabolism and function.Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination.PDK1 plays a vital role on hematopoietic stem cell function.S-Nitrosylation inhibits the kinase activity of tomato phosphoinositide-dependent kinase 1 (PDK1).Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment.
P2860
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P2860
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
@en
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
@nl
type
label
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
@en
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
@nl
prefLabel
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
@en
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
@nl
P2093
P2860
P356
P1433
P1476
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
@en
P2093
Ayaz Najafov
Frederick Simeons
J Simon C Arthur
Janet C Patterson-Kane
Laste Stojanovski
Pierre C McCarthy
Rachel Toth
Ram K C Venigalla
Rosemary Clarke
Victoria A McGuire
P2860
P304
P356
10.1038/EMBOJ.2013.40
P407
P577
2013-03-05T00:00:00Z