Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival.
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Tropomyosin-related kinase B/brain derived-neurotrophic factor signaling pathway as a potential therapeutic target for colorectal cancerTreatment of Cancer Pain by Targeting CytokinesBiomarkers for circadian rhythm disruption independent of time of daySortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasionBDNF is associated with SFRP1 expression in luminal and basal-like breast cancer cell lines and primary breast cancer tissues: a novel role in tumor suppression?A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor markerBrain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancerChemotherapy-induced dynamic gene expression changes in vivo are prognostic in ovarian cancer.Brain-derived neurotrophic factor (BDNF) -TrKB signaling modulates cancer-endothelial cells interaction and affects the outcomes of triple negative breast cancer.The neurobiology of cancer pain.Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling.TrkC expression predicts favorable clinical outcome in invasive ductal carcinoma of breast independent of NT-3 expression.Upregulation of TrkB promotes epithelial-mesenchymal transition and anoikis resistance in endometrial carcinoma.Targeted PDT agent eradicates TrkC expressing tumors via photodynamic therapy (PDT)A TrkB-STAT3-miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cellsExtensive rewiring of epithelial-stromal co-expression networks in breast cancerPro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein.More expression of BDNF associates with lung squamous cell carcinoma and is critical to the proliferation and invasion of lung cancer cells.Anti-apoptotic role and clinical relevance of neurotrophins in diffuse large B-cell lymphomasLarge oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease.p75 neurotrophin receptor and pro-BDNF promote cell survival and migration in clear cell renal cell carcinoma.Psychoactive drugs influence brain-derived neurotrophic factor and neurotrophin 4/5 levels in the serum of colorectal cancer patientsPI3K and MAPK pathways mediate the BDNF/TrkB-increased metastasis in neuroblastoma.Influence of GRPR and BDNF/TrkB signaling on the viability of breast and gynecologic cancer cellsNeurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis.Curcumin Ameliorates Cisplatin-Induced Nephrotoxicity and Potentiates Its Anticancer Activity in SD Rats: Potential Role of Curcumin in Breast Cancer Chemotherapy.Uncovering the role of brain-derived neurotrophic factor/tyrosine kinase receptor B signaling in head and neck malignancies.Effects of Chinese medicinal herbs on expression of brain-derived Neurotrophic factor (BDNF) and its interaction with human breast cancer MDA-MB-231 cells and endothelial HUVECsNeurotrophin signaling in cancer stem cells.BDNF/TrkB Signaling as a Potential Novel Target in Pediatric Brain Tumors: Anticancer Activity of Selective TrkB Inhibition in Medulloblastoma Cells.Receptor Level Mechanisms Are Required for Epidermal Growth Factor (EGF)-stimulated Extracellular Signal-regulated Kinase (ERK) Activity PulsesNerve fibers infiltrate the tumor microenvironment and are associated with nerve growth factor production and lymph node invasion in breast cancer.More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells.The TrkB+ cancer stem cells contribute to post-chemotherapy recurrence of triple-negative breast cancers in an orthotopic mouse model.Extracellular cleavage of the p75 neurotrophin receptor is implicated in its pro-survival effect in breast cancer cells.Therapeutic Potentials of BDNF/TrkB in Breast Cancer; Current Status and Perspectives.Organotypic culture of normal, dysplastic and squamous cell carcinoma-derived oral cell lines reveals loss of spatial regulation of CD44 and p75 NTR in malignancy.Knockdown of BDNF suppressed invasion of HepG2 and HCCLM3 cells, a mechanism associated with inactivation of RhoA or Rac1 and actin skeleton disorganization.Dual inhibition of BDNF/TrkB and autophagy: a promising therapeutic approach for colorectal cancerCooperation of neurotrophin receptor TrkB and Her2 in breast cancer cells facilitates brain metastases
P2860
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P2860
Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Brain-derived neurotrophic fac ...... o inhibit tumor cell survival.
@en
Brain-derived neurotrophic fac ...... o inhibit tumor cell survival.
@nl
type
label
Brain-derived neurotrophic fac ...... o inhibit tumor cell survival.
@en
Brain-derived neurotrophic fac ...... o inhibit tumor cell survival.
@nl
prefLabel
Brain-derived neurotrophic fac ...... o inhibit tumor cell survival.
@en
Brain-derived neurotrophic fac ...... o inhibit tumor cell survival.
@nl
P2093
P1476
Brain-derived neurotrophic fac ...... to inhibit tumor cell survival
@en
P2093
Elsa Vanhecke
Eric Adriaenssens
Hubert Hondermarck
Nathalie Berteaux
Samuel Meignan
Stéphanie Verbeke
Victor Nurcombe
Xuefen Le Bourhis
P304
P356
10.1158/1078-0432.CCR-10-1890
P407
P577
2011-02-24T00:00:00Z