Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy.
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Thermodynamic Stabilization of the Folded Domain of Prion Protein Inhibits Prion Infection in VivoDe novo generation of a transmissible spongiform encephalopathy by mouse transgenesisPrion formation, but not clearance, is supported by protein misfolding cyclic amplification.Prion replication without host adaptation during interspecies transmissions.Accelerated high fidelity prion amplification within and across prion species barriers.Prion diseases and their biochemical mechanisms.Transgenic mice expressing porcine prion protein resistant to classical scrapie but susceptible to sheep bovine spongiform encephalopathy and atypical scrapieTracing conformational transition of abnormal prion proteins during interspecies transmission by using novel antibodies.Molecular analysis of the abnormal prion protein during coinfection of mice by bovine spongiform encephalopathy and a scrapie agent.Coinfecting prion strains compete for a limiting cellular resource.Inter-allelic prion propagation reveals conformational relationships among a multitude of [PSI] strains.Human prion strain selection in transgenic mice.Retrograde transport of transmissible mink encephalopathy within descending motor tracts.The prion hypothesis: from biological anomaly to basic regulatory mechanism.Identification of inter-species transmission of prion strains.Tracking protein aggregate interactions.Conformational transformation and selection of synthetic prion strains.Prion interference is due to a reduction in strain-specific PrPSc levels.Transmission and adaptation of chronic wasting disease to hamsters and transgenic mice: evidence for strains.Mouse-adapted scrapie strains 139A and ME7 overcome species barrier to induce experimental scrapie in hamsters and changed their pathogenic features.Molecular behaviors of "CH1641-like" sheep scrapie isolates in ovine transgenic mice (TgOvPrP4).Host Determinants of Prion Strain Diversity Independent of Prion Protein Genotype.Stabilization of a prion strain of synthetic origin requires multiple serial passagesDisease-associated prion protein in neural and lymphoid tissues of mink (Mustela vison) inoculated with transmissible mink encephalopathy.Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay.Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.Selective amplification of classical and atypical prions using modified protein misfolding cyclic amplification.Convergent replication of mouse synthetic prion strains.The prion strain phenomenon: molecular basis and unprecedented features.The reconstitution of mammalian prion infectivity de novo.Detection and control of prion diseases in food animals.Role of Prion Replication in the Strain-dependent Brain Regional Distribution of PrionsPrion interference with multiple prion isolatesChanges in prion replication environment cause prion strain mutationCo-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristicsCross currents in protein misfolding disorders: interactions and therapy.Divergent prion strain evolution driven by PrPC expression level in transgenic mice.Heterogeneity of abnormal prion protein (PrP(Sc)) in murine scrapie prions determined by PrP(Sc)-specific monoclonal antibodies.A closer look at prion strains: characterization and important implications.The structure of human prions: from biology to structural models-considerations and pitfalls.
P2860
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P2860
Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Adaptation and selection of pr ...... smissible mink encephalopathy.
@en
Adaptation and selection of pr ...... smissible mink encephalopathy.
@nl
type
label
Adaptation and selection of pr ...... smissible mink encephalopathy.
@en
Adaptation and selection of pr ...... smissible mink encephalopathy.
@nl
prefLabel
Adaptation and selection of pr ...... smissible mink encephalopathy.
@en
Adaptation and selection of pr ...... smissible mink encephalopathy.
@nl
P2860
P50
P1433
P1476
Adaptation and selection of pr ...... smissible mink encephalopathy.
@en
P2093
P2860
P304
P356
10.1128/JVI.74.12.5542-5547.2000
P407
P577
2000-06-01T00:00:00Z