Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.

Item
http://www.wikidata.org/entity/Q39596478
The biology of proteostasis in aging and disease.Large-scale screen for modifiers of ataxin-3-derived polyglutamine-induced toxicity in Drosophila.RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndromeCAG expansion induces nucleolar stress in polyglutamine diseases.Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stressBiological significance of the importin-β family-dependent nucleocytoplasmic transport pathways.From pathways to targets: understanding the mechanisms behind polyglutamine disease.Assessing a peptidylic inhibitor-based therapeutic approach that simultaneously suppresses polyglutamine RNA- and protein-mediated toxicities in patient cells and Drosophila.The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1-PKB/Akt signalling.GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer's disease.Divalproex sodium modulates nuclear localization of ataxin-3 and prevents cellular toxicity caused by expanded ataxin-3.A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases.Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
P2860

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.

Item
http://www.wikidata.org/entity/Q39596478
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Expanded polyglutamine domain ...... isease protein via exportin-1.
@en
Expanded polyglutamine domain ...... isease protein via exportin-1.
@nl
type
label
Expanded polyglutamine domain ...... isease protein via exportin-1.
@en
Expanded polyglutamine domain ...... isease protein via exportin-1.
@nl
prefLabel
Expanded polyglutamine domain ...... isease protein via exportin-1.
@en
Expanded polyglutamine domain ...... isease protein via exportin-1.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Expanded polyglutamine domain ...... disease protein via exportin-1
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698