The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

Item
http://www.wikidata.org/entity/Q39602310
8-Methoxypsoralen is a competitive inhibitor of glutathione S-transferase P1-1A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts.Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibitionA new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.JLK1486, a N,N-[(8-hydroxyquinoline)methyl]-substituted benzylamine analogue, inhibits melanoma proliferation and induces autophagy.Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines.The FAD-dependent glycerol-3-phosphate dehydrogenase of Giardia duodenalis: an unconventional enzyme that interacts with the g14-3-3 and it is a target of the antitumoral compound NBDHEX.6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol: a promising new anticancer compound.Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases.Glutathione S-transferase P1-1 as a target for mesothelioma treatment.Glutathione S -transferase π: a potential role in antitumor therapy
P2860

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

Item
http://www.wikidata.org/entity/Q39602310
description
2011 nî lūn-bûn
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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2011年论文
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2011年论文
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name
The glutathione transferase in ...... cy against malignant melanoma.
@en
The glutathione transferase in ...... cy against malignant melanoma.
@nl
type
label
The glutathione transferase in ...... cy against malignant melanoma.
@en
The glutathione transferase in ...... cy against malignant melanoma.
@nl
prefLabel
The glutathione transferase in ...... cy against malignant melanoma.
@en
The glutathione transferase in ...... cy against malignant melanoma.
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P1433
P1476
P2093
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P433
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The glutathione transferase in ...... acy against malignant melanoma
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P2093
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P31
P356
10.1016/J.EJCA.2010.12.008
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P478
P50
P577
P698