Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity. - Wikidata - wikimedia - TriplyDB

Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity.

Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity.

http://www.wikidata.org/entity/Q39606015

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A virtual lymph node model to dissect the requirements for T-cell activation by synapses and kinapses.T-cell receptor gene therapy--ready to go viral?Selector function of MHC I molecules is determined by protein plasticity Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome Simultaneous alignment and clustering of peptide data using a Gibbs sampling approach.Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.Characterization of binding specificities of bovine leucocyte class I molecules: impacts for rational epitope discovery.Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule Targeting of cancer neoantigens with donor-derived T cell receptor repertoires.HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeni Identification and HLA-tetramer-validation of human CD4+ and CD8+ T cell responses against HCMV proteins IE1 and IE2.TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes.CD8+ TCR Bias and Immunodominance in HIV-1 Infection.Identification of human leukemia antigen A*0201-restricted epitopes derived from epidermal growth factor pathway substrate number 8 The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study.A modern approach for epitope prediction: identification of foot-and-mouth disease virus peptides binding bovine leukocyte antigen (BoLA) class I molecules.A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-1*04:01, SLA-2*04:01, and SLA-3*04:01.Establishing the pig as a large animal model for vaccine development against human cancer HLA-B7-restricted islet epitopes are differentially recognized in type 1 diabetic children and adults and form weak peptide-HLA complexes.Immunoinformatics and epitope prediction in the age of genomic medicine.HIV control through a single nucleotide on the HLA-B locus.Prediction and in vitro verification of potential CTL epitopes conserved among PRRSV-2 strains.Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope.Modification of a tumor antigen determinant to improve peptide/MHC stability is associated with increased immunogenicity and cross-priming a larger fraction of CD8+ T cells Discovering naturally processed antigenic determinants that confer protective T cell immunity.Antigen-stimulated CD4 T cell expansion can be limited by their grazing of peptide-MHC complexes.Dipeptides promote folding and peptide binding of MHC class I molecules Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection.Development of a peptide-based vaccine targeting TMPRSS2:ERG fusion-positive prostate cancer.Going Pro to enhance T-cell immunogenicity: easy as π?Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocul Potentiation of T Cell Stimulatory Activity by Chemical Fixation of a Weak Peptide-MHC Complex Bioinformatics for cancer immunotherapy target discovery.HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma.Analogue peptides for the immunotherapy of human acute myeloid leukemia.Sizing up the key determinants of the CD8(+) T cell response.HIV-1 adaptation to NK cell-mediated immune pressure.Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells.Current tools for predicting cancer-specific T cell immunity.Differential presentation of endogenous and exogenous hepatitis B surface antigens influences priming of CD8(+) T cells in an epitope-specific manner.

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P2860

Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity.

http://www.wikidata.org/entity/Q39606015

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Peptide-MHC class I stability ...... ffinity of CTL immunogenicity.

@en

Peptide-MHC class I stability ...... ffinity of CTL immunogenicity.

@nl

type

label

Peptide-MHC class I stability ...... ffinity of CTL immunogenicity.

@en

Peptide-MHC class I stability ...... ffinity of CTL immunogenicity.

@nl

prefLabel

Peptide-MHC class I stability ...... ffinity of CTL immunogenicity.

@en

Peptide-MHC class I stability ...... ffinity of CTL immunogenicity.

@nl

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European Journal of Immunology

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Peptide-MHC class I stability ...... ffinity of CTL immunogenicity.

@en

P2093

Gustav Roder

http://www.w3.org/2001/XMLSchema#string

Ida Dalgaard Pedersen

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Michael Rasmussen

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Mikael Sørensen

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Søren Buus

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P2860

Reliable prediction of T-cell epitopes using neural networks with novel sequence representations

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.

Steric hindrance and fast dissociation explain the lack of immunogenicity of the minor histocompatibility HA-1Arg Null allele

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100

NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence

One-pot, mix-and-read peptide-MHC tetramers

HLA class I binding 9mer peptides from influenza A virus induce CD4 T cell responses

Selecting informative data for developing peptide-MHC binding predictors using a query by committee approach.

Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses.

Amino-terminal alteration of the HLA-A*0201-restricted human immunodeficiency virus pol peptide increases complex stability and in vitro immunogenicity

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1405-1416

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scholarly article

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10.1002/EJI.201141774

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6

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42

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Mikkel Harndahl

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2012-06-01T00:00:00Z

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225280514

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22678897

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