CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells.
about
Siglecs as sensors of self in innate and adaptive immune responsesSiglecs and immune regulationInfection, inflammation and host carbohydrates: a Glyco-Evasion HypothesisCD22 and Siglec-G in B cell function and toleranceAntigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169A phase 2 study of inotuzumab ozogamicin in patients with indolent B-cell non-Hodgkin lymphoma refractory to rituximab alone, rituximab and chemotherapy, or radioimmunotherapy.Siglec-mediated regulation of immune cell function in disease.Click and pick: identification of sialoside analogues for siglec-based cell targetingActivatory and inhibitory Fcγ receptors augment rituximab-mediated internalization of CD20 independent of signaling via the cytoplasmic domainDynamics of memory B-cell populations in blood, lymph nodes, and bone marrow during antiretroviral therapy and envelope boosting in simian immunodeficiency virus SIVmac251-infected rhesus macaques.A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicitySiglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions.B-cell maturation antigen is modified by a single N-glycan chain that modulates ligand binding and surface retention.Glycobiology of immune responsesCD22 and autoimmune disease.Targeting CD22 in B-cell malignancies: current status and clinical outlook.CD22 and Siglec-G regulate inhibition of B-cell signaling by sialic acid ligand binding and control B-cell tolerance.In pursuit of a moving target: nanotherapeutics for the treatment of non-Hodgkin B-cell lymphoma.Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches.The HB22.7-vcMMAE antibody-drug conjugate has efficacy against non-Hodgkin lymphoma mouse xenografts with minimal systemic toxicity.Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells.DropArray™, a wall-less 96-well plate for uptake and immunofluorescence microscopy, confirms CD22 recycles.Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas.Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis.The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophiliaThe Consequences of Multiple Simultaneous C-Type Lectin-Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN.Regulation of B cell functions by the sialic acid-binding receptors siglec-G and CD22.Molecular basis of human CD22 function and therapeutic targeting.IBC's 21st Annual Antibody Engineering and 8th Annual Antibody Therapeutics International Conferences and 2010 Annual Meeting of the Antibody Society. December 5-9, 2010, San Diego, CA USA.CD22 Ligands on a Natural N-Glycan Scaffold Efficiently Deliver Toxins to B-Lymphoma Cells.Domain II of Pseudomonas Exotoxin Is Critical for Efficacy of Bolus Doses in a Xenograft Model of Acute Lymphoblastic Leukemia.CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity
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P2860
CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
@zh-cn
name
CD22 is a recycling receptor t ...... somal compartments of B cells.
@en
CD22 is a recycling receptor t ...... somal compartments of B cells.
@nl
type
label
CD22 is a recycling receptor t ...... somal compartments of B cells.
@en
CD22 is a recycling receptor t ...... somal compartments of B cells.
@nl
prefLabel
CD22 is a recycling receptor t ...... somal compartments of B cells.
@en
CD22 is a recycling receptor t ...... somal compartments of B cells.
@nl
P2093
P2860
P356
P1476
CD22 is a recycling receptor t ...... somal compartments of B cells.
@en
P2093
James C Paulson
Mary K O'Reilly
P2860
P304
P356
10.4049/JIMMUNOL.1003005
P407
P577
2010-12-22T00:00:00Z