Pink-eyed dilution protein controls the processing of tyrosinase.
about
Oculocutaneous albinismLocalization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 functionMelanosomes--dark organelles enlighten endosomal membrane transportInvolvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanomaIntravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cellsTriazine-based tyrosinase inhibitors identified by chemical genetic screening.Identification of quinolines that inhibit melanogenesis by altering tyrosinase family trafficking.Basis for enhanced barrier function of pigmented skin.Spectrum of candidate gene mutations associated with Indian familial oculocutaneous and ocular albinism.Different approaches for assaying melanosome transferAn intracellular anion channel critical for pigmentation.Conserved function of medaka pink-eyed dilution in melanin synthesis and its divergent transcriptional regulation in gonads among vertebratesFunctional interactions between OCA2 and the protein complexes BLOC-1, BLOC-2, and AP-3 inferred from epistatic analyses of mouse coat pigmentationReduced glutathione disrupts the intracellular trafficking of tyrosinase and tyrosinase-related protein-1 but not dopachrome tautomerase and Pmel17 to melanosomes, which results in the attenuation of melanization.Informed reasoning: repositioning of nitisinone to treat oculocutaneous albinismA nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2(p)) in mice.Mechanisms of protein delivery to melanosomes in pigment cells.Hair follicle pigmentationHuman melanocyte biology, toxicology, and pathology.Tyrosinase maturation through the mammalian secretory pathway: bringing color to life.Molecular genetic studies and delineation of the oculocutaneous albinism phenotype in the Pakistani populationReport of a novel OCA2 gene mutation and an investigation of OCA2 variants on melanoma risk in a familial melanoma pedigree.A Genetic Mechanism for Convergent Skin Lightening during Recent Human Evolution.Management of melanoma families.Influence of melanosome dynamics on melanoma drug sensitivity.Molecular outcomes, clinical consequences, and genetic diagnosis of Oculocutaneous Albinism in Pakistani population.How are proliferation and differentiation of melanocytes regulated?Genetic variation in regulatory DNA elements: the case of OCA2 transcriptional regulation.Ion transport in pigmentation.Loss of Oca2 disrupts the unfolded protein response and increases resistance to endoplasmic reticulum stress in melanocytes.Pigmented-MDCK (P-MDCK) cell line with tunable melanin expression: an in vitro model for the outer blood-retinal barrierPink-eyed dilution protein modulates arsenic sensitivity and intracellular glutathione metabolism.Variation in Hsp70-1A Expression Contributes to Skin Color DiversityIntracellular composition of fatty acid affects the processing and function of tyrosinase through the ubiquitin-proteasome pathway.The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding.Changes in the proliferation and differentiation of neonatal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine.Correction of defective early tyrosinase processing by bafilomycin A1 and monensin in pink-eyed dilution melanocytes.oca2 Regulation of chromatophore differentiation and number is cell type specific in zebrafish.Inheritance of a novel mutated allele of the OCA2 gene associated with high incidence of oculocutaneous albinism in a Polynesian community.Characterization of OCA2 cDNA in different porcine breeds and analysis of its potential effect on skin pigmentation in a red Iberian strain.
P2860
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P2860
Pink-eyed dilution protein controls the processing of tyrosinase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Pink-eyed dilution protein controls the processing of tyrosinase.
@en
Pink-eyed dilution protein controls the processing of tyrosinase.
@nl
type
label
Pink-eyed dilution protein controls the processing of tyrosinase.
@en
Pink-eyed dilution protein controls the processing of tyrosinase.
@nl
prefLabel
Pink-eyed dilution protein controls the processing of tyrosinase.
@en
Pink-eyed dilution protein controls the processing of tyrosinase.
@nl
P2860
P356
P1476
Pink-eyed dilution protein controls the processing of tyrosinase
@en
P2093
Prashiela Manga
P2860
P304
P356
10.1091/MBC.02-02-0022.
P50
P577
2002-06-01T00:00:00Z