Anterograde axonal transport of AAV2-GDNF in rat basal ganglia - Wikidata - wikimedia - TriplyDB

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

http://www.wikidata.org/entity/Q39628466

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Biology of adeno-associated viral vectors in the central nervous system Gene-based therapy of Parkinson's Disease: Translation from animal model to human clinical trial employing convection enhanced delivery Glial-derived neurotrophic factor gene transfer for Parkinson's disease: anterograde distribution of AAV2 vectors in the primate brain Axonal transport of AAV9 in nonhuman primate brain.Transgenic expression of human glial cell line-derived neurotrophic factor from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease.Supraspinal gene transfer by intrathecal adeno-associated virus serotype 5.Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles.SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE.Functional neuroprotection and efficient regulation of GDNF using destabilizing domains in a rodent model of Parkinson's disease.Safety and tolerability of magnetic resonance imaging-guided convection-enhanced delivery of AAV2-hAADC with a novel delivery platform in nonhuman primate striatum.Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model.Presynaptic Inputs to Any CNS Projection Neuron Identified by Dual Recombinant Virus Infection Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease Direct and retrograde transduction of nigral neurons with AAV6, 8, and 9 and intraneuronal persistence of viral particles Gene therapy for misfolding protein diseases of the central nervous system.Transgene expression in target-defined neuron populations mediated by retrograde infection with adeno-associated viral vectors Adeno-associated virus type 6 is retrogradely transported in the non-human primate brain.Impact of age and vector construct on striatal and nigral transgene expression.AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction.Revelation in the neuroprotective functions of rasagiline and selegiline: the induction of distinct genes by different mechanisms.Gene therapy for the treatment of Parkinson's disease: the nature of the biologics expands the future indications Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy.Trans-neuronal transduction of spinal neurons following cortical injection and anterograde axonal transport of a bicistronic AAV1 vector Perspective on the Road toward Gene Therapy for Parkinson's Disease.Viral vector-based tools advance knowledge of basal ganglia anatomy and physiology.Convection-Enhanced Delivery.MR-guided parenchymal delivery of adeno-associated viral vector serotype 5 in non-human primate brain.Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse.Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery Moving forward toward a cure for Parkinson's: neuropathology of the nigrostriatal pathway determines the location of growth factor delivery.Axonal transport of adeno-associated viral vectors is serotype-dependent.Cypermethrin-induced nigrostriatal dopaminergic neurodegeneration alters the mitochondrial function: a proteomics study.Engineered viral vectors for functional interrogation, deconvolution, and manipulation of neural circuits.Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys.

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P2860

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

http://www.wikidata.org/entity/Q39628466

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

@zh-cn

name

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

@en

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia.

@nl

type

label

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

@en

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia.

@nl

prefLabel

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

@en

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia.

@nl

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Molecular Therapy

P1476

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

@en

P2093

Adrian P Kells

http://www.w3.org/2001/XMLSchema#string

Agnieszka Ciesielska

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Gabriele Mittermeyer

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John Forsayeth

http://www.w3.org/2001/XMLSchema#string

Krystof S Bankiewicz

http://www.w3.org/2001/XMLSchema#string

Piotr Hadaczek

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P2860

Gene therapy in Parkinson's disease: rationale and current status

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

Neuroprotective and neurorestorative properties of GDNF.

Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats.

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys.

Optimized cannula design and placement for convection-enhanced delivery in rat striatum

Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.

Transient demyelination increases the efficiency of retrograde AAV transduction

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model.

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922-927

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10.1038/MT.2010.248

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5

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19

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21102559

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3098627

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