HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2.
about
Eukaryotic initiation factor 2α--a downstream effector of mammalian target of rapamycin--modulates DNA repair and cancer response to treatmentThe PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells.Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.Control of oncogenesis by eIF2α phosphorylation: implications in PTEN and PI3K-Akt signaling and tumor treatment.GCN2 deficiency ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and myocardial oxidative stress.Triazolo[4,5]pyrimidines as Validated General Control Nonderepressible 2 (GCN2) Protein Kinase Inhibitors Reduce Growth of Leukemia Cells
P2860
HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
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name
HDAC pharmacological inhibitio ...... he eIF2α kinases PKR and GCN2.
@en
HDAC pharmacological inhibitio ...... he eIF2α kinases PKR and GCN2.
@nl
type
label
HDAC pharmacological inhibitio ...... he eIF2α kinases PKR and GCN2.
@en
HDAC pharmacological inhibitio ...... he eIF2α kinases PKR and GCN2.
@nl
prefLabel
HDAC pharmacological inhibitio ...... he eIF2α kinases PKR and GCN2.
@en
HDAC pharmacological inhibitio ...... he eIF2α kinases PKR and GCN2.
@nl
P2093
P2860
P356
P1433
P1476
HDAC pharmacological inhibitio ...... he eIF2α kinases PKR and GCN2.
@en
P2093
Andreas I Papadakis
Antonis E Koromilas
Kamindla Rajesh
Philippos Peidis
P2860
P304
P356
10.18632/AGING.100216
P577
2010-10-01T00:00:00Z