Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.

Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.

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http://www.wikidata.org/entity/Q39641906
Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptorQSAR based model for discriminating EGFR inhibitors and non-inhibitors using Random forestHomology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification.Anchor-based classification and type-C inhibitors for tyrosine kinases.Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer.Epidermal growth factor receptor inhibitors: a patent review (2010 - present).Discovery of Potent c-MET Inhibitors with New Scaffold Having Different Quinazoline, Pyridine and Tetrahydro-Pyridothienopyrimidine Headgroups.Recent Development of the Second and Third Generation Irreversible Epidermal Growth Factor Receptor Inhibitors.6-Aryl and heterocycle quinazoline derivatives as potent EGFR inhibitors with improved activity toward gefitinib-sensitive and -resistant tumor cell lines.Synthesis and Evaluation of Biological and Antitumor Activities of Tetrahydrobenzothieno[2,3-d]Pyrimidine Derivatives as Novel Inhibitors of FGFR1.CovalentDock: automated covalent docking with parameterized covalent linkage energy estimation and molecular geometry constraints.Design, Synthesis, and Biological Activity of Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine Derivatives as Anti-Inflammatory Agents.Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer Activities.Biomass-involved synthesis of N-substituted benzofuro[2,3-d]pyrimidine-4-amines and biological evaluation as novel EGFR tyrosine kinase inhibitors.Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors
P2860

Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.

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http://www.wikidata.org/entity/Q39641906
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Design and synthesis of tetrah ...... tor group for maximal potency.
@en
Design and synthesis of tetrah ...... tor group for maximal potency.
@nl
type
label
Design and synthesis of tetrah ...... tor group for maximal potency.
@en
Design and synthesis of tetrah ...... tor group for maximal potency.
@nl
prefLabel
Design and synthesis of tetrah ...... tor group for maximal potency.
@en
Design and synthesis of tetrah ...... tor group for maximal potency.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Design and synthesis of tetrah ...... ptor group for maximal potency
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698