TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia.
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Regulation of Endothelial Adherens Junctions by Tyrosine PhosphorylationCo-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signalingA novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation.Impacts of environmental toxicants on male reproductive dysfunctionReactive oxygen species in inflammation and tissue injuryEndothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK ActivationPharmacological Inactivation of Src Family Kinases Inhibits LPS-Induced TNF-α Production in PBMC of Patients with Behçet's DiseaseNEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signalingBacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the endothelial paracellular pathway.Lipopolysaccharides up-regulate Kir6.1/SUR2B channel expression and enhance vascular KATP channel activity via NF-kappaB-dependent signalingActivation of c-Src: a hub for exogenous pro-oxidant-mediated activation of Toll-like receptor 4 signalingSrc-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers.The adaptor CRADD/RAIDD controls activation of endothelial cells by proinflammatory stimuli.Alcohol-induced interactive phosphorylation of Src and toll-like receptor regulates the secretion of inflammatory mediators by human astrocytes.Innate immune function of the adherens junction protein p120-catenin in endothelial response to endotoxinMediators of Tyrosine Phosphorylation in Innate Immunity: From Host Defense to Inflammation onto Oncogenesis.Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation.Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injuryHarvesting, identification and barrier function of human lung microvascular endothelial cellsDifferent contributions of clathrin- and caveolae-mediated endocytosis of vascular endothelial cadherin to lipopolysaccharide-induced vascular hyperpermeability.Anthrax lethal toxin-mediated disruption of endothelial VE-cadherin is attenuated by inhibition of the Rho-associated kinase pathwaySalvianolic Acid B Ameliorates Lipopolysaccharide-Induced Albumin Leakage from Rat Mesenteric Venules through Src-Regulated Transcelluar Pathway and Paracellular Pathway.Lipopolysaccharide-induced caveolin-1 phosphorylation-dependent increase in transcellular permeability precedes the increase in paracellular permeability.Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's DiseaseRegulation of β-adrenergic receptor trafficking and lung microvascular endothelial cell permeability by Rab5 GTPase.NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does notTRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.Tubedown regulation of retinal endothelial permeability signaling pathways.The intracerebroventricular injection of rimonabant inhibits systemic lipopolysaccharide-induced lung inflammation.Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-α: Crosstalk with p38 Signaling.Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells.Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulationADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.Novel phosphatidylethanolamine derivatives accumulate in circulation in hyperlipidemic ApoE-/- mice and activate platelets via TLR2.The role of cytoskeleton in the regulation of vascular endothelial barrier function.Epidermal growth factor-like repeats of thrombospondins activate phospholipase Cgamma and increase epithelial cell migration through indirect epidermal growth factor receptor activationRhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa BEndogenous endothelial cell signaling systems maintain vascular stability.Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edemaEGFR mediates hyperlipidemia-induced renal injury via regulating inflammation and oxidative stress: the detrimental role and mechanism of EGFR activation.
P2860
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P2860
TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
TLR4 signaling is coupled to S ...... lung microvascular endothelia.
@en
TLR4 signaling is coupled to S ...... lung microvascular endothelia.
@nl
type
label
TLR4 signaling is coupled to S ...... lung microvascular endothelia.
@en
TLR4 signaling is coupled to S ...... lung microvascular endothelia.
@nl
prefLabel
TLR4 signaling is coupled to S ...... lung microvascular endothelia.
@en
TLR4 signaling is coupled to S ...... lung microvascular endothelia.
@nl
P2093
P2860
P356
P1476
TLR4 signaling is coupled to S ...... lung microvascular endothelia.
@en
P2093
Alan S Cross
Daniel J Angelini
Douglas D Bannerman
Guanjun Xia
Shiqi Yang
Simeon E Goldblum
Stefanie N Vogel
P2860
P304
13437-13449
P356
10.1074/JBC.M707986200
P407
P577
2008-03-07T00:00:00Z