Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
about
Understanding CRY2 interactions for optical control of intracellular signaling.Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions.PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors.Model based analysis of the heterogeneity in the tumour size dynamics differentiates vemurafenib, dabrafenib and trametinib in metastatic melanoma.Light-Regulated Protein Kinases Based on the CRY2-CIB1 System.Optogenetically controlled protein kinases for regulation of cellular signaling.Type II RAF inhibitor causes superior ERK pathway suppression compared to type I RAF inhibitor in cells expressing different BRAF mutant types recurrently found in lung cancer.
P2860
Q41701350-EACC4544-2CFB-41D7-B44C-18D21B958D1FQ42361482-AB95BB66-E367-4B6B-AFB6-5F98848E7957Q47142625-41ACA9EF-2F7D-4AB6-AF86-524A606BE6DBQ47174361-D48C83D9-BF08-4FC3-B2A5-A98693EA9F6EQ50183354-32074632-5B48-4C1D-964D-0004EF4D2827Q50421174-7907E05B-F4F7-4884-B8A0-0A208F0CE26FQ54115748-6CA68D8F-8D8A-410E-9961-FD20392C49CB
P2860
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
@en
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
@nl
type
label
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
@en
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
@nl
prefLabel
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
@en
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
@nl
P2093
P2860
P356
P1433
P1476
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
@en
P2093
Anne Müller
Claire V Chatelle
Désirée Hövermann
Gerald Radziwill
Hanna J Wagner
Wilfried Weber
P2860
P2888
P356
10.1038/SREP23713
P407
P577
2016-03-30T00:00:00Z