Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.
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PHD2: from hypoxia regulation to disease progressionNon-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop.Secretome profiling with antibody microarrays.Suppression of glioma progression by Egln3Differential regulation of breast cancer-associated genes by progesterone receptor isoforms PRA and PRB in a new bi-inducible breast cancer cell line.Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2.Development of lymphoproliferative diseases by hypoxia inducible factor-1alpha is associated with prolonged lymphocyte survival.Short hairpin RNA gene silencing of prolyl hydroxylase-2 with a minicircle vector improves neovascularization of hindlimb ischemia.Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemiaAmphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway.Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.Amphiregulin stimulates liver regeneration after small-for-size mouse liver transplantation.Tumor PHD2 expression is correlated with clinical features and prognosis of patients with HCC receiving liver resectionProlyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathwayHypoxia-inducible factor-mediated induction of WISP-2 contributes to attenuated progression of breast cancer.Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer.Prolyl 4-hydroxylases, master regulators of the hypoxia response.Prolyl 4 hydroxylase: a critical target in the pathophysiology of diseases.PRL-3 promotes gastric cancer migration and invasion through a NF-κB-HIF-1α-miR-210 axis.Prolyl-4-hydroxylase 2 enhances hypoxia-induced glioblastoma cell death by regulating the gene expression of hypoxia-inducible factor-αTherapeutic inhibition of prolyl hydroxylase domain-containing enzymes in surgery: putative applications and challenges.Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas.Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer.The PHD2 oxygen sensor paves the way to metastasis.Stimulation of Interferon-Stimulated Gene 20 by Thyroid Hormone Enhances Angiogenesis in Liver Cancer.Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-β1 processing.pVHL-mediated degradation of HIF-2α regulates estrogen receptor α expression in normoxic breast cancer cells.Cellular prion protein and γ-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch.Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury.Hypoxic Signalling in Tumour Stroma.Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion.Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growthPolymorphisms in and breast cancer sutarsceptibility in Chinese women: a case-control study
P2860
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P2860
Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Prolyl-4-hydroxylase PHD2- and ...... butes to breast tumorigenesis.
@en
Prolyl-4-hydroxylase PHD2- and ...... butes to breast tumorigenesis.
@nl
type
label
Prolyl-4-hydroxylase PHD2- and ...... butes to breast tumorigenesis.
@en
Prolyl-4-hydroxylase PHD2- and ...... butes to breast tumorigenesis.
@nl
prefLabel
Prolyl-4-hydroxylase PHD2- and ...... butes to breast tumorigenesis.
@en
Prolyl-4-hydroxylase PHD2- and ...... butes to breast tumorigenesis.
@nl
P2093
P2860
P356
P1433
P1476
Prolyl-4-hydroxylase PHD2- and ...... ibutes to breast tumorigenesis
@en
P2093
G Camenisch
G Kristiansen
M R Bordoli
R H Wenger
S Hausladen
P2860
P2888
P304
P356
10.1038/ONC.2010.433
P407
P577
2010-09-20T00:00:00Z