Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression. - Wikidata - wikimedia - TriplyDB

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression.

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression.

http://www.wikidata.org/entity/Q39655180

about

Systems biology of cisplatin resistance: past, present and future DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells The genomic landscape of testicular germ cell tumours: from susceptibility to treatment.Efficacy of targeted drugs in germ cell cancer cell lines with differential cisplatin sensitivity.Drugging the Cancers Addicted to DNA Repair.Heterogeneous nuclear ribonucleoprotein K is associated with poor prognosis and regulates proliferation and apoptosis in bladder cancer.Quantification and expert evaluation of evidence for chemopredictive biomarkers to personalize cancer treatment.Targeting DNA repair pathways for cancer treatment: what's new?Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition.Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells Association between ERCC1 and XPA expression and polymorphisms and the response to cisplatin in testicular germ cell tumours.Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity.Intensive chemotherapy as salvage treatment for solid tumors: focus on germ cell cancer.ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform Human CD4+CD25+ regulatory T cells are sensitive to low dose cyclophosphamide: implications for the immune response.Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours.Expression of domains for protein-protein interaction of nucleotide excision repair proteins modifies cancer cell sensitivity to platinum derivatives and genomic stability.A Review of ERCC1 Gene in Bladder Cancer: Implications for Carcinogenesis and Resistance to Chemoradiotherapy Excision Repair Cross-complementation Group 1 is a Prognostic Biomarker in Patients with Colorectal Cancer Receiving Chemotherapy.Carbon ion beam combined with cisplatin effectively disrupts triple negative breast cancer stem-like cells in vitro.Binding interaction of HMGB4 with cisplatin-modified DNA.JWA reverses cisplatin resistance via the CK2-XRCC1 pathway in human gastric cancer cells.Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links.Cancer stem cells and chemoresistance: The smartest survives the raid A quantitative mass spectrometry-based approach for assessing the repair of 8-methoxypsoralen-induced DNA interstrand cross-links and monoadducts in mammalian cells.The timing of caffeic acid treatment with cisplatin determines sensitization or resistance of ovarian carcinoma cell lines.The prognostic value of DNA damage level in peripheral blood lymphocytes of chemotherapy-naïve patients with germ cell cancer.Cisplatin resistance in germ cell tumours: models and mechanisms.Prognostic and predictive factors in patients treated with chemotherapy for advanced urothelial cancer: where do we stand?Higher expression of XPF is a critical factor in intrinsic chemotherapy resistance of human renal cell carcinoma.Curcumin downregulates p38 MAPK-dependent X-ray repair cross-complement group 1 (XRCC1) expression to enhance cisplatin-induced cytotoxicity in human lung cancer cells.Single nucleotide polymorphisms in DNA repair genes and putative cancer risk.An Overview on Predictive Biomarkers of Testicular Germ Cell Tumors.Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair.A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites.Cisplatin Toxicity in Dorsal Root Ganglion Neurons Is Relieved by Meclizine via Diminution of Mitochondrial Compromise and Improved Clearance of DNA Damage.Increased expression of DNA repair gene XPF enhances resistance to hydroxycamptothecin in bladder cancer.Pharmacogenomic considerations in the treatment of muscle-invasive bladder cancer.Diagnostic delay in oncology: a case report of metastatic seminoma.

P2860

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P2860

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression.

http://www.wikidata.org/entity/Q39655180

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年论文

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name

Cisplatin sensitivity of testi ...... and low ERCC1-XPF expression.

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Cisplatin sensitivity of testi ...... and low ERCC1-XPF expression.

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type

label

Cisplatin sensitivity of testi ...... and low ERCC1-XPF expression.

@en

Cisplatin sensitivity of testi ...... and low ERCC1-XPF expression.

@nl

prefLabel

Cisplatin sensitivity of testi ...... and low ERCC1-XPF expression.

@en

Cisplatin sensitivity of testi ...... and low ERCC1-XPF expression.

@nl

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Molecular Cancer

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Cisplatin sensitivity of testi ...... and low ERCC1-XPF expression.

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Andrea Piée-Staffa

http://www.w3.org/2001/XMLSchema#string

Astrid Schneider

http://www.w3.org/2001/XMLSchema#string

Beate Köberle

http://www.w3.org/2001/XMLSchema#string

Bernd Kaina

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Jürgen Thomale

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Svetlana Usanova

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Ulrike Sied

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P2860

Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

Checkpoint signaling from a single DNA interstrand crosslink

Activity of individual ERCC1 and XPF subunits in DNA nucleotide excision repair

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis

The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks

Cisplatin: mode of cytotoxic action and molecular basis of resistance

Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines.

Cell cycle checkpoint abrogator UCN-01 inhibits DNA repair: association with attenuation of the interaction of XPA and ERCC1 nucleotide excision repair proteins.

Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions.

XPA protein as a limiting factor for nucleotide excision repair and UV sensitivity in human cells.

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3098011

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