Towards synthesis of monoterpenes and derivatives using synthetic biologySYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicalsMetabolomics methods for the synthetic biology of secondary metabolismPurification and structural determination of SCB1, a gamma-butyrolactone that elicits antibiotic production in Streptomyces coelicolor A3(2)MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic modelsTranscriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2)Ribosylhopane, a novel bacterial hopanoid, as precursor of C35 bacteriohopanepolyols in Streptomyces coelicolor A3(2)Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor.A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor.The dynamic architecture of the metabolic switch in Streptomyces coelicolor.Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolorGenome-wide inference of regulatory networks in Streptomyces coelicolor.Convergent transcription in the butyrolactone regulon in Streptomyces coelicolor confers a bistable genetic switch for antibiotic biosynthesis.Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clustersCharacterisation of a natural variant of the γ-butyrolactone signalling receptor.Design-based re-engineering of biosynthetic gene clusters: plug-and-play in practice.Noncoding RNA of glutamine synthetase I modulates antibiotic production in Streptomyces coelicolor A3(2).Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products.A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesisFunctional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block.redD and actII-ORF4, pathway-specific regulatory genes for antibiotic production in Streptomyces coelicolor A3(2), are transcribed in vitro by an RNA polymerase holoenzyme containing sigma hrdD.Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli.Minimum Information about a Biosynthetic Gene cluster.antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clustersSynthetic Biology of Natural Products.Gamma-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation.Detecting sequence homology at the gene cluster level with MultiGeneBlast.Exploring the metabolic state of microorganisms using metabolomics.Computational tools for the synthetic design of biochemical pathways.Modeling challenges in the synthetic biology of secondary metabolism.Steps towards the synthetic biology of polyketide biosynthesis.Synthetic biology advances for pharmaceutical production.Butyrolactone signalling circuits for synthetic biology.Bioinformatics for the synthetic biology of natural products: integrating across the Design-Build-Test cycle.A turning point for natural product discovery--ESF-EMBO research conference: synthetic biology of antibiotic production.The future of industrial antibiotic production: from random mutagenesis to synthetic biology.Metabolomic characterization of the salt stress response in Streptomyces coelicolor.The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerusSeparating the wheat from the chaff: a prioritisation pipeline for the analysis of metabolomics datasets.
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