Bioanalysis of alectinib and metabolite M4 in human plasma, cross-validation and impact on PK assessment.
about
Effect of alectinib on cardiac electrophysiology: results from intensive electrocardiogram monitoring from the pivotal phase II NP28761 and NP28673 studies.Model-Based Assessments of CYP-Mediated Drug-Drug Interaction Risk of Alectinib: Physiologically Based Pharmacokinetic Modeling Supported Clinical Development.LC-MS/MS determination of alectinib and its major human metabolite M4 in human urine: prevention of nonspecific binding.Effect of the Wetting Agent Sodium Lauryl Sulfate on the Pharmacokinetics of Alectinib: Results From a Bioequivalence Study in Healthy Subjects.Exposure-response analysis of alectinib in crizotinib-resistant ALK-positive non-small cell lung cancer.Clinical Drug-Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib.Effect of Food and Esomeprazole on the Pharmacokinetics of Alectinib, a Highly Selective ALK Inhibitor, in Healthy Subjects.Method validation studies and an inter-laboratory cross validation study of lenvatinib assay in human plasma using LC-MS/MS.
P2860
Q38938203-2601855B-48AE-4141-AC97-A68800482B4EQ47333263-70C395F1-B78D-4267-89AE-BD9B6B0F6D56Q51147243-321A1926-2592-4A01-9031-8547590F8B45Q51280223-B8B2B492-48C4-4DCC-A39A-BB340C13EA85Q53684267-64A4FBB4-00CF-43D9-8274-232DF4A27B44Q54178349-8D28F5BF-0F04-4D4F-AF14-2091D901C4EEQ55017122-64C9240A-1988-4F44-A743-73F4F053058DQ55617920-F4CAD011-F575-4221-811D-F5C5C3FD8072
P2860
Bioanalysis of alectinib and metabolite M4 in human plasma, cross-validation and impact on PK assessment.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Bioanalysis of alectinib and m ...... n and impact on PK assessment.
@en
Bioanalysis of alectinib and m ...... n and impact on PK assessment.
@nl
type
label
Bioanalysis of alectinib and m ...... n and impact on PK assessment.
@en
Bioanalysis of alectinib and m ...... n and impact on PK assessment.
@nl
prefLabel
Bioanalysis of alectinib and m ...... n and impact on PK assessment.
@en
Bioanalysis of alectinib and m ...... n and impact on PK assessment.
@nl
P2093
P2860
P356
P1433
P1476
Bioanalysis of alectinib and m ...... n and impact on PK assessment.
@en
P2093
Daniela Fraier
Elena Guerini
Katja Heinig
Kazuhiro Miya
Peter N Morcos
Surendra Bansal
Tomonori Kamei
P2860
P304
P356
10.4155/BIO-2016-0068
P577
2016-06-22T00:00:00Z