Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism.
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Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viabilityThe threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control.Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form.Isotopomer profiling of Leishmania mexicana promastigotes reveals important roles for succinate fermentation and aspartate uptake in tricarboxylic acid cycle (TCA) anaplerosis, glutamate synthesis, and growth.Functional characterization of TbMCP5, a conserved and essential ADP/ATP carrier present in the mitochondrion of the human pathogen Trypanosoma brucei.Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.Characterization of two mitochondrial flavin adenine dinucleotide-dependent glycerol-3-phosphate dehydrogenases in Trypanosoma brucei.Quantitative NMR for bioanalysis and metabolomics.Combining reverse genetics and nuclear magnetic resonance-based metabolomics unravels trypanosome-specific metabolic pathways.Mitochondrial pyruvate carrier in Trypanosoma brucei.Two NAD-linked redox shuttles maintain the peroxisomal redox balance in Saccharomyces cerevisiae.ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma.Dynamic nuclear polarization facilitates monitoring of pyruvate metabolism in Trypanosoma brucei.De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions.Pharmacological Metabolomics in Trypanosomes
P2860
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P2860
Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Ablation of succinate producti ...... tle and to proline metabolism.
@en
Ablation of succinate producti ...... tle and to proline metabolism.
@nl
type
label
Ablation of succinate producti ...... tle and to proline metabolism.
@en
Ablation of succinate producti ...... tle and to proline metabolism.
@nl
prefLabel
Ablation of succinate producti ...... tle and to proline metabolism.
@en
Ablation of succinate producti ...... tle and to proline metabolism.
@nl
P2093
P2860
P50
P356
P1476
Ablation of succinate producti ...... ttle and to proline metabolism
@en
P2093
Frédéric Bringaud
Gilles Gouspillou
Jane Hubert
Jean-Michel Franconi
Marc Biran
Nicolas Plazolles
Pauline Morand
P2860
P304
32312-32324
P356
10.1074/JBC.M110.124917
P407
P577
2010-08-11T00:00:00Z