Specific inactivation of inhibitory sequences in the 5' end of the human papillomavirus type 16 L1 open reading frame results in production of high levels of L1 protein in human epithelial cells.
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Papillomavirus genome structure, expression, and post-transcriptional regulationThe DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein.The 3' region of human papillomavirus type 16 early mRNAs decrease expression.Generalized substitution of isoencoding codons shortens the duration of papillomavirus L1 protein expression in transiently gene-transfected keratinocytes due to cell differentiationA downstream polyadenylation element in human papillomavirus type 16 L2 encodes multiple GGG motifs and interacts with hnRNP H.Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3Viable adenovirus vaccine prototypes: high-level production of a papillomavirus capsid antigen from the major late transcriptional unit.A splicing enhancer in the E4 coding region of human papillomavirus type 16 is required for early mRNA splicing and polyadenylation as well as inhibition of premature late gene expression.Gene codon composition determines differentiation-dependent expression of a viral capsid gene in keratinocytes in vitro and in vivo.RNA Binding Proteins that Control Human Papillomavirus Gene Expression.Heterogeneous Nuclear Ribonucleoprotein C Proteins Interact with the Human Papillomavirus Type 16 (HPV16) Early 3'-Untranslated Region and Alleviate Suppression of HPV16 Late L1 mRNA Splicing.Productive Lifecycle of Human Papillomaviruses that Depends Upon Squamous Epithelial Differentiation.An HPV 16 L1-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice.The RNA stability regulator HuR regulates L1 protein expression in vivo in differentiating cervical epithelial cells.tRNASer(CGA) differentially regulates expression of wild-type and codon-modified papillomavirus L1 genes.Suppression of HPV-16 late L1 5'-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs.Codon usage roles in human papillomavirus.Splicing and Polyadenylation of Human Papillomavirus Type 16 mRNAs.Human papillomavirus type 16 E2 protein transcriptionally activates the promoter of a key cellular splicing factor, SF2/ASF.Mutational inactivation of two distinct negative RNA elements in the human papillomavirus type 16 L2 coding region induces production of high levels of L2 in human cells.Polypyrimidine tract binding protein induces human papillomavirus type 16 late gene expression by interfering with splicing inhibitory elements at the major late 5' splice site, SD3632Keratinocyte Differentiation-Dependent Human Papillomavirus Gene Regulation.The alternative splicing factor hnRNP A1 is up-regulated during virus-infected epithelial cell differentiation and binds the human papillomavirus type 16 late regulatory element.Identification of an hnRNP A1-dependent splicing silencer in the human papillomavirus type 16 L1 coding region that prevents premature expression of the late L1 gene.Mechanisms regulating expression of the HPV 31 L1 and L2 capsid proteins and pseudovirion entry.HPV-16 E2 contributes to induction of HPV-16 late gene expression by inhibiting early polyadenylation.Immunogenic assessment of plant-produced human papillomavirus type 16 L1/L2 chimaeras.The DNA damage response activates HPV16 late gene expression at the level of RNA processing.Optimizing a Human Papillomavirus Type 16 L1-Based Chimaeric Gene for Expression in PlantsN-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro
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Specific inactivation of inhibitory sequences in the 5' end of the human papillomavirus type 16 L1 open reading frame results in production of high levels of L1 protein in human epithelial cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Specific inactivation of inhib ...... ein in human epithelial cells.
@en
Specific inactivation of inhib ...... ein in human epithelial cells.
@nl
type
label
Specific inactivation of inhib ...... ein in human epithelial cells.
@en
Specific inactivation of inhib ...... ein in human epithelial cells.
@nl
prefLabel
Specific inactivation of inhib ...... ein in human epithelial cells.
@en
Specific inactivation of inhib ...... ein in human epithelial cells.
@nl
P2093
P2860
P1433
P1476
Specific inactivation of inhib ...... ein in human epithelial cells.
@en
P2093
Brian Collier
Daniel Oberg
Stefan Schwartz
Xiaomin Zhao
P2860
P304
P356
10.1128/JVI.76.6.2739-2752.2002
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P577
2002-03-01T00:00:00Z