Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16.
about
BitterDB: a database of bitter compoundsOrigin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in AfricaSnooker structure-based pharmacophore model explains differences in agonist and blocker binding to bitter receptor hTAS2R39Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicinInsights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptorIdentification of key amino acid residues in the hTGR5-nomilin interaction and construction of its binding model.Amino acid derivatives as bitter taste receptor (T2R) blockers.Coarse-grained/molecular mechanics of the TAS2R38 bitter taste receptor: experimentally-validated detailed structural prediction of agonist binding.Principal component analysis of binding energies for single-point mutants of hT2R16 bound to an agonist correlate with experimental mutant cell response6-methoxyflavanones as bitter taste receptor blockers for hTAS2R39Rapid Expansion of Phenylthiocarbamide Non-Tasters among Japanese Macaques.Do polymorphisms in chemosensory genes matter for human ingestive behavior?The good taste of peptides.Development of a cultured cell-based human-taste evaluation system.The Bitter Taste Receptor TAS2R16 Achieves High Specificity and Accommodates Diverse Glycoside Ligands by using a Two-faced Binding Pocket.Structural basis of activation of bitter taste receptor T2R1 and comparison with Class A G-protein-coupled receptors (GPCRs)Establishment of a new cell-based assay to measure the activity of sweeteners in fluorescent food extracts.Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation.Amino acid residues of bitter taste receptor TAS2R16 that determine sensitivity in primates to β-glycosides.Agonist Binding to Chemosensory Receptors: A Systematic Bioinformatics AnalysisFunctional diversity of bitter taste receptor TAS2R16 in primates.Chimeric yeast G-protein α subunit harboring a 37-residue C-terminal gustducin-specific sequence is functional in Saccharomyces cerevisiae.Probing the Evolutionary History of Human Bitter Taste Receptor Pseudogenes by Restoring Their Function.Natural product modulators of human sensations and mood: molecular mechanisms and therapeutic potential.Structure-function relationships of the human bitter taste receptor hTAS2R1: insights from molecular modeling studies.Molecular biology of mammalian bitter taste receptors. A review
P2860
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P2860
Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Characterization of the beta-D ...... itter taste receptor hTAS2R16.
@en
Characterization of the beta-D ...... itter taste receptor hTAS2R16.
@nl
type
label
Characterization of the beta-D ...... itter taste receptor hTAS2R16.
@en
Characterization of the beta-D ...... itter taste receptor hTAS2R16.
@nl
prefLabel
Characterization of the beta-D ...... itter taste receptor hTAS2R16.
@en
Characterization of the beta-D ...... itter taste receptor hTAS2R16.
@nl
P2093
P2860
P356
P1476
Characterization of the beta-D ...... itter taste receptor hTAS2R16.
@en
P2093
Katsuyoshi Masuda
Keisuke Ito
Masaji Ishiguro
Shinji Matsuo
Taishi Sugawara
Takanobu Sakurai
Takumi Misaka
Takuya Kobayashi
Tomiko Asakura
P2860
P304
28373-28378
P356
10.1074/JBC.M110.144444
P407
P577
2010-07-06T00:00:00Z