A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.
about
DNA repair targeted therapy: The past or future of cancer treatment?CHK2 kinase in the DNA damage response and beyondComparative analysis of radiosensitizers for K-RAS mutant rectal cancersThe protein phosphatase 2A inhibitor LB100 sensitizes ovarian carcinoma cells to cisplatin-mediated cytotoxicityElevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrumThe Expression and Clinical Outcome of pCHK2-Thr68 and pCDC25C-Ser216 in Breast Cancer.Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication.Serine/threonine phosphatases in the DNA damage response and cancer.Beyond ATM: the protein kinase landscape of the DNA damage response.Checkpoint control and cancer.Bimodal regulation of p21(waf1) protein as function of DNA damage levels.Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis.Akt confers cisplatin chemoresistance in human gynecological carcinoma cells by modulating PPM1D stability.Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.The G2 checkpoint-a node-based molecular switch.CHK2 stability is regulated by the E3 ubiquitin ligase SIAH2.Checkpoint kinase 2 is required for efficient immunoglobulin diversification.Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiencyHydroxyurea induces chromosomal damage in G2 and enhances the clastogenic effect of mitomycin C in Fanconi anemia cells.A Boolean network model of the FA/BRCA pathway.
P2860
Q26768679-F853753D-EC75-4527-8FC0-AB79B58A9665Q34977480-60167E62-7C80-41E1-8991-B98A15797D60Q35070685-51F94EFA-FB30-4DBB-97F8-F9D5DF319179Q36019903-975CB11D-A539-4FE2-866B-642960BBE819Q36080515-8CE7802C-8AEA-4F9C-8330-F93DE05F11EBQ36403630-0835ED5B-0256-4B12-A38A-B8E9854DA20CQ37465400-CDD3FB04-62A6-4698-A093-93D7F0E4962AQ37698893-C3658D2E-73A5-4E48-9718-613547D56539Q37788536-89E1EB73-88A4-48E6-8257-E00C089D8BF2Q37875377-3C8C4CA3-2F5A-4C9A-9596-9735900B8CD5Q37941374-820915C4-0BB8-4032-8EAA-870A5FE27D7CQ38930942-C3640AE7-CC69-4AB3-8900-82842EB99804Q38943445-A0CBE5F2-59FF-486D-B82A-738E25742131Q38963051-9EAF9E7C-A609-4925-989A-7C61D1A27824Q39543888-722B9C1B-6006-43C9-AD5D-B08BFF46347BQ42231430-E12B9540-AC88-4C3A-8C5F-D858BC733D8DQ42487278-CA71473F-A698-4B80-8E3A-537F2CD6C7FBQ42541714-2E4815FE-B91E-4B00-9205-116385DA2EE2Q42771888-64C1D86A-5825-4C7A-A309-5F1DF1776188Q46597959-6FA84CD4-DBFC-48C9-A2D7-1FA408F89A75Q48014596-302CD9AC-39E2-4B0D-B502-C98909F2294A
P2860
A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
A protein phosphatase feedback ...... in the absence of DNA damage.
@en
A protein phosphatase feedback ...... in the absence of DNA damage.
@nl
type
label
A protein phosphatase feedback ...... in the absence of DNA damage.
@en
A protein phosphatase feedback ...... in the absence of DNA damage.
@nl
prefLabel
A protein phosphatase feedback ...... in the absence of DNA damage.
@en
A protein phosphatase feedback ...... in the absence of DNA damage.
@nl
P1476
A protein phosphatase feedback ...... e in the absence of DNA damage
@en
P2093
Domenico Delia
Enrico Fontanella
P304
P356
10.1016/J.BBAMCR.2010.06.002
P577
2010-06-22T00:00:00Z