A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility.
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Sequence and analysis of the genome of the pathogenic yeast Candida orthopsilosisEmerging Threats in Antifungal-Resistant Fungal PathogensCandida infections, causes, targets, and resistance mechanisms: traditional and alternative antifungal agentsClinical perspectives on echinocandin resistance among Candida speciesEchinocandin resistance: an emerging clinical problem?Antifungal Therapy: New Advances in the Understanding and Treatment of MycosisGenetic Basis of Antifungal Drug ResistanceParadoxical growth of Candida albicans in the presence of caspofungin is associated with multiple cell wall rearrangements and decreased virulence.Genotypic and phenotypic properties of Candida parapsilosis sensu strictu strains isolated from different geographic regions and body sites.Novel FKS mutations associated with echinocandin resistance in Candida species.Breakthrough invasive candidiasis in patients on micafungin.Target enzyme mutations confer differential echinocandin susceptibilities in Candida kefyrDifferential Aspergillus lentulus echinocandin susceptibilities are Fksp independent.Candida guilliermondii and other species of candida misidentified as Candida famata: assessment by vitek 2, DNA sequencing analysis, and matrix-assisted laser desorption ionization-time of flight mass spectrometry in two global antifungal surveillanFKS2 mutations associated with decreased echinocandin susceptibility of Candida glabrata following anidulafungin therapy.Micafungin in the treatment of invasive candidiasis and invasive aspergillosisNew Fks hot spot for acquired echinocandin resistance in Saccharomyces cerevisiae and its contribution to intrinsic resistance of Scedosporium speciesEchinocandin susceptibility testing of Candida isolates collected during a 1-year period in Sweden.Species distribution and susceptibility profile to fluconazole, voriconazole and MXP-4509 of 551 clinical yeast isolates from a Romanian multi-centre study.Susceptibility to echinocandins of Candida spp. strains isolated in Italy assessed by European Committee for Antimicrobial Susceptibility Testing and Clinical Laboratory Standards Institute broth microdilution methods.Fluconazole and Voriconazole Resistance in Candida parapsilosis Is Conferred by Gain-of-Function Mutations in MRR1 Transcription Factor Gene.Interlaboratory reproducibility of Etest amphotericin B and caspofungin yeast susceptibility testing and comparison with the CLSI method.Rapid development of Candida krusei echinocandin resistance during caspofungin therapy.Progress in antifungal susceptibility testing of Candida spp. by use of Clinical and Laboratory Standards Institute broth microdilution methods, 2010 to 2012The presence of an FKS mutation rather than MIC is an independent risk factor for failure of echinocandin therapy among patients with invasive candidiasis due to Candida glabrata.Echinocandin Resistance in Candida.Epidemiology and echinocandin susceptibility of Candida parapsilosis sensu lato species isolated from bloodstream infections at a Spanish university hospital.Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints.Treatment of invasive candidiasis in the elderly: a reviewOutcome of Candida Parapsilosis Complex Infections Treated with Caspofungin in Children.Antifungal drug resistance mechanisms.Anidulafungin versus caspofungin in a mouse model of candidiasis caused by anidulafungin-susceptible Candida parapsilosis isolates with different degrees of caspofungin susceptibilityCurrent perspectives on echinocandin class drugs.Candida parapsilosis: a review of its epidemiology, pathogenesis, clinical aspects, typing and antimicrobial susceptibility.Pharmacokinetics, antifungal activity and clinical efficacy of anidulafungin in the treatment of fungal infections.Evaluating the role of prophylaxis in the management of invasive fungal infections in patients with hematologic malignancy.ECIL-3 classical diagnostic procedures for the diagnosis of invasive fungal diseases in patients with leukaemia.Treatment of Candida famata bloodstream infections: case series and review of the literature.Echinocandins: production and applications.Current status of antifungal resistance and its impact on clinical practice.
P2860
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P2860
A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A naturally occurring proline- ...... d echinocandin susceptibility.
@en
A naturally occurring proline- ...... d echinocandin susceptibility.
@nl
type
label
A naturally occurring proline- ...... d echinocandin susceptibility.
@en
A naturally occurring proline- ...... d echinocandin susceptibility.
@nl
prefLabel
A naturally occurring proline- ...... d echinocandin susceptibility.
@en
A naturally occurring proline- ...... d echinocandin susceptibility.
@nl
P2093
P2860
P356
P1476
A naturally occurring proline- ...... d echinocandin susceptibility.
@en
P2093
David S Perlin
Guillermo Garcia-Effron
Santosh K Katiyar
Steven Park
Thomas D Edlind
P2860
P304
P356
10.1128/AAC.00262-08
P407
P577
2008-04-28T00:00:00Z