Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor.
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Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependentMuscle-specific signaling mechanism that links actin dynamics to serum response factor.Nuclear actin and actin-binding proteins in the regulation of transcription and gene expressionThe transcriptional activity of Sox9 in chondrocytes is regulated by RhoA signaling and actin polymerizationMutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic diseaseMegakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genesA method for rapidly screening functionality of actin mutants and tagged actinsNuclear F-actin formation and reorganization upon cell spreading.Nuclear actin modulates cell motility via transcriptional regulation of adhesive and cytoskeletal genes.Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1Subcellular localization of multiple PREP2 isoforms is regulated by actin, tubulin, and nuclear exportPhosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with DblMyocardin-Related Transcription Factor A Activation by Competition with WH2 Domain Proteins for Actin Binding.MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activationGEF-H1 functions in apical constriction and cell intercalations and is essential for vertebrate neural tube closure.Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear.Zyxin is involved in thrombin signaling via interaction with PAR-1 receptorFramework to function: mechanosensitive regulators of gene transcriptionThe core and conserved role of MAL is homeostatic regulation of actin levels.Dominant negative mutant actins identified in flightless Drosophila can be classified into three classes.Actin is a component of the compensation mechanism in pseudorabies virus virions lacking the major tegument protein VP22.Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of nuclear factor-kappaB.Actin-mediated gene expression in neurons: the MRTF-SRF connection.Linking actin dynamics and gene transcription to drive cellular motile functions.Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytesActive maintenance of nuclear actin by importin 9 supports transcription.Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells.A role for beta-actin in RNA polymerase III transcriptionDepletion of nuclear actin is a key mediator of quiescence in epithelial cells.β- and γ-Actins in the nucleus of human melanoma A375 cellsNucleoplasmic beta-actin exists in a dynamic equilibrium between low-mobility polymeric species and rapidly diffusing populations.Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistanceSUMOylation of nuclear actinCytoplasmic YY1 is associated with increased smooth muscle-specific gene expression: implications for neonatal pulmonary hypertensionEffect of overexpression of β- and γ-actin isoforms on actin cytoskeleton organization and migration of human colon cancer cellsLpd depletion reveals that SRF specifies radial versus tangential migration of pyramidal neurons.Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells.Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cellsNuclear actin and myosins in adenovirus infection.
P2860
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P2860
Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Mutant actins demonstrate a ro ...... tion by serum response factor.
@en
Mutant actins demonstrate a ro ...... tion by serum response factor.
@nl
type
label
Mutant actins demonstrate a ro ...... tion by serum response factor.
@en
Mutant actins demonstrate a ro ...... tion by serum response factor.
@nl
prefLabel
Mutant actins demonstrate a ro ...... tion by serum response factor.
@en
Mutant actins demonstrate a ro ...... tion by serum response factor.
@nl
P2860
P356
P1476
Mutant actins demonstrate a ro ...... tion by serum response factor.
@en
P2093
Athanassia Sotiropoulos
Guido Posern
P2860
P304
P356
10.1091/MBC.02-05-0068
P577
2002-12-01T00:00:00Z