Cysteine 723 in the C-linker segment confers oxidative inhibition of hERG1 potassium channels.
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The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel DeactivationS-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivationGlobal analysis reveals families of chemical motifs enriched for HERG inhibitorsOxidative modulation of voltage-gated potassium channels.Analyzing cell physiology in C. elegans with fluorescent ratiometric reporters.Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channelPyTMs: a useful PyMOL plugin for modeling common post-translational modifications.Hydrogen peroxide differentially affects activity in the pre-Bötzinger complex and hippocampusMetabolic stress, reactive oxygen species, and arrhythmia.Aging effects on QT interval: Implications for cardiac safety of antipsychotic drugs.Cytoplasmic domains and voltage-dependent potassium channel gating.Redox control of cardiac excitability.Atrial fibrillation in the elderly: the potential contribution of reactive oxygen species.Looking into a conceptual framework of ROS-miRNA-atrial fibrillation.A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K(+) channels in carbon monoxide-induced proarrhythmic early afterdepolarizations.C-terminal dimerization activates the nociceptive transduction channel transient receptor potential vanilloid 1.Diesel Exhaust Worsens Cardiac Conduction Instability in Dobutamine-Challenged Wistar-Kyoto and Spontaneously Hypertensive Rats.Cysteines control the N- and C-linker-dependent gating of KCNH1 potassium channels.Interactions between the N-terminal tail and the gating machinery of hERG K⁺ channels both in closed and open/inactive states.Oxidative stress fine-tunes the dance of hERG K+ channels.CO-independent modification of K+ channels by tricarbonyldichlororuthenium(II) dimer (CORM-2).Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels.Class 3 inhibition of hERG K+ channel by caffeic acid phenethyl ester (CAPE) and curcumin.Suppression of hERG K current and cardiac action potential prolongation by 4-hydroxynonenal via dual mechanisms
P2860
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P2860
Cysteine 723 in the C-linker segment confers oxidative inhibition of hERG1 potassium channels.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Cysteine 723 in the C-linker s ...... n of hERG1 potassium channels.
@en
Cysteine 723 in the C-linker s ...... n of hERG1 potassium channels.
@nl
type
label
Cysteine 723 in the C-linker s ...... n of hERG1 potassium channels.
@en
Cysteine 723 in the C-linker s ...... n of hERG1 potassium channels.
@nl
prefLabel
Cysteine 723 in the C-linker s ...... n of hERG1 potassium channels.
@en
Cysteine 723 in the C-linker s ...... n of hERG1 potassium channels.
@nl
P2093
P2860
P1476
Cysteine 723 in the C-linker s ...... on of hERG1 potassium channels
@en
P2093
Guido Gessner
Katrin Kolbe
Roland Schönherr
Toshinori Hoshi
P2860
P304
P356
10.1113/JPHYSIOL.2010.192468
P407
P577
2010-06-14T00:00:00Z