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Replication and expansion of trinucleotide repeats in yeast

Replication and expansion of trinucleotide repeats in yeast

http://www.wikidata.org/entity/Q39700490

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Winemaking and bioprocesses strongly shaped the genetic diversity of the ubiquitous yeast Torulaspora delbrueckii Comparative genomics and molecular dynamics of DNA repeats in eukaryotes Mechanistic features of CAG*CTG repeat contractions in cultured cells revealed by a novel genetic assay Inverted repeat-stimulated sister-chromatid exchange events are RAD1-independent but reduced in a msh2 mutant.Advances in mechanisms of genetic instability related to hereditary neurological diseases.Methods to detect replication-dependent and replication-independent DNA structure-induced genetic instability The balancing act of DNA repeat expansions The hidden side of unstable DNA repeats: Mutagenesis at a distance Molecular mechanism of resolving trinucleotide repeat hairpin by helicases Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.DNA Replication Dynamics of the GGGGCC Repeat of the C9orf72 Gene.The Rtt109 histone acetyltransferase facilitates error-free replication to prevent CAG/CTG repeat contractions.Evolutionary consequences of a large duplication event in Trypanosoma brucei: chromosomes 4 and 8 are partial duplicons Effects of mutations in SGS1 and in genes functionally related to SGS1 on inverted repeat-stimulated spontaneous unequal sister-chromatid exchange in yeast Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae Expanded CAG/CTG repeat DNA induces a checkpoint response that impacts cell proliferation in Saccharomyces cerevisiae.Evaluation of CAG repeat length of androgen receptor expressing cells in human testes showing different pictures of spermatogenic impairment.Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments.NuA4 initiates dynamic histone H4 acetylation to promote high-fidelity sister chromatid recombination at postreplication gaps.Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract.An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae Replication fork regression in repetitive DNAs.Double-strand breaks in the myotonic dystrophy type 1 and the fragile X syndrome triplet repeat sequences induce different types of mutations in DNA flanking sequences in Escherichia coli.On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease.Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability.Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination.Repeat instability during DNA repair: Insights from model systems Overcoming natural replication barriers: differential helicase requirements.Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis Altered replication in human cells promotes DMPK (CTG)(n) · (CAG)(n) repeat instability Evidence for chromosome fragility at the frataxin locus in Friedreich ataxia.Repeat instability: mechanisms of dynamic mutations.Oligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability.Mature microsatellites: mechanisms underlying dinucleotide microsatellite mutational biases in human cells.Replication fork stalling at natural impediments.Features of trinucleotide repeat instability in vivo.Inhibition of DNA synthesis facilitates expansion of low-complexity repeats: is strand slippage stimulated by transient local depletion of specific dNTPs?

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Replication and expansion of trinucleotide repeats in yeast

http://www.wikidata.org/entity/Q39700490

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

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2003年學術文章

@zh-hant

name

Replication and expansion of trinucleotide repeats in yeast

@en

Replication and expansion of trinucleotide repeats in yeast.

@nl

type

label

Replication and expansion of trinucleotide repeats in yeast

@en

Replication and expansion of trinucleotide repeats in yeast.

@nl

prefLabel

Replication and expansion of trinucleotide repeats in yeast

@en

Replication and expansion of trinucleotide repeats in yeast.

@nl

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MCB.23.4.1349-1357.2003

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Molecular and Cellular Biology

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Replication and expansion of trinucleotide repeats in yeast

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George M Samadashwily

http://www.w3.org/2001/XMLSchema#string

Maria M Krasilnikova

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Richard Pelletier

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Robert Lahue

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P2860

A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells

CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae

Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats

Clamping down on clamps and clamp loaders--the eukaryotic replication factor C

The distribution of the numbers of mutants in bacterial populations

A genetic system for direct selection of gene-positive clones during recombinational cloning in yeast

DNA secondary structure: a common and causative factor for expansion in human disease.

Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases

Transcription through a simple DNA repeat blocks replication elongation

Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism.

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1349-1357

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10.1128/MCB.23.4.1349-1357.2003

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Sergei M Mirkin

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