Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.

about

Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78).HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.Parkinson disease related ATP13A2 evolved early in animal evolution.

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Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.

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http://www.wikidata.org/entity/Q39706189

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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name

Protection against Mitochondri ...... ipid Binding Sites in ATP13A2.

@en

Protection against Mitochondri ...... ipid Binding Sites in ATP13A2.

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type

Item

label

Protection against Mitochondri ...... ipid Binding Sites in ATP13A2.

@en

Protection against Mitochondri ...... ipid Binding Sites in ATP13A2.

@nl

prefLabel

Protection against Mitochondri ...... ipid Binding Sites in ATP13A2.

@en

Protection against Mitochondri ...... ipid Binding Sites in ATP13A2.

@nl

P1476

Protection against Mitochondri ...... Lipid Binding Sites in ATP13A2

@en

P2093

Chris van den Haute

http://www.w3.org/2001/XMLSchema#string

Jan Eggermont

http://www.w3.org/2001/XMLSchema#string

Seyma Demirsoy

http://www.w3.org/2001/XMLSchema#string

Shaun Martin

http://www.w3.org/2001/XMLSchema#string

Tine Holemans

http://www.w3.org/2001/XMLSchema#string

Veerle Baekelandt

http://www.w3.org/2001/XMLSchema#string

P2860

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

Self and nonself: how autophagy targets mitochondria and bacteria

PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions.

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes.

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

A lipid switch unlocks Parkinson's disease-associated ATP13A2

ATP13A2 regulates mitochondrial bioenergetics through macroautophagy

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

Unlocking ATP13A2/PARK9 activity

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9531917

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scholarly article

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10.1155/2016/9531917

http://www.w3.org/2001/XMLSchema#string

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2016

http://www.w3.org/2001/XMLSchema#string

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Patrizia Agostinis

Peter Vangheluwe

Sarah van Veen

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2016-03-17T00:00:00Z

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298797331

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27073711

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P921

metal poisoning

P932

4814700

http://www.w3.org/2001/XMLSchema#string

Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.

about

P2860

P2860

Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.

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