Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia.
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Melatonin as a potential anticarcinogen for non-small-cell lung cancerMelatonin prevents myeloperoxidase heme destruction and the generation of free iron mediated by self-generated hypochlorous acidMelatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic MicrogliaMelatonin suppresses hypoxia-induced migration of HUVECs via inhibition of ERK/Rac1 activation.2-Hydroxymelatonin, a Predominant Hydroxylated Melatonin Metabolite in Plants, Shows Antitumor Activity against Human Colorectal Cancer Cells.Melatonin Reduces Angiogenesis in Serous Papillary Ovarian Carcinoma of Ethanol-Preferring RatsOral Mucositis: Melatonin Gel an Effective New Treatment.Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride.Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin.The role of androgens on hypoxia-inducible factor (HIF)-1α-induced angiogenesis and on the survival of ischemically challenged skin flaps in a rat model.Melatonin anticancer effects: reviewUpregulation of miRNA3195 and miRNA374b Mediates the Anti-Angiogenic Properties of Melatonin in Hypoxic PC-3 Prostate Cancer Cells.Low Molecular Weight Fucoidan Inhibits Tumor Angiogenesis through Downregulation of HIF-1/VEGF Signaling under Hypoxia.Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization.Effect of Melatonin in Epithelial Mesenchymal Transition Markers and Invasive Properties of Breast Cancer Stem Cells of Canine and Human Cell LinesMelatonin rescues cardiovascular dysfunction during hypoxic development in the chick embryoSynthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors.Expression and significance of hypoxia-inducible factor-1α and MDR1/P-glycoprotein in laryngeal carcinoma tissue and hypoxic Hep-2 cells.Effect of melatonin on tumor growth and angiogenesis in xenograft model of breast cancer.Melatonin Mediates Protective Effects against Kainic Acid-Induced Neuronal Death through Safeguarding ER Stress and Mitochondrial Disturbance.Melatonin as a natural ally against oxidative stress: a physicochemical examination.Beneficial actions of melatonin in the management of viral infections: a new use for this "molecular handyman"?A review of the molecular aspects of melatonin's anti-inflammatory actions: recent insights and new perspectives.Action of melatonin on squamous cell carcinoma and other tumors of the oral cavity (Review).Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes.Melatonin as a treatment for gastrointestinal cancer: a review.Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1 promoter in primordial follicles.Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α.Regulation of vascular endothelial growth factor by melatonin in human breast cancer cells.Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor model.The melatonin immunomodulatory actions in radiotherapy.The psychoneuroendocrine-immunotherapy of cancer: Historical evolution and clinical results.Melatonin as a Promising Agent to Treat Ovarian Cancer: Molecular Mechanisms.Melatonin prevents human pancreatic carcinoma cell PANC-1-induced human umbilical vein endothelial cell proliferation and migration by inhibiting vascular endothelial growth factor expression.Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells.Melatonin and Hippo Pathway: Is There Existing Cross-Talk?Effects of melatonin on HIF-1α and VEGF expression and on the invasive properties of hepatocarcinoma cells.3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1α) in the tumor microenvironmentsInhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells.
P2860
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P2860
Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Melatonin suppresses tumor ang ...... a stabilization under hypoxia.
@en
Melatonin suppresses tumor ang ...... a stabilization under hypoxia.
@nl
type
label
Melatonin suppresses tumor ang ...... a stabilization under hypoxia.
@en
Melatonin suppresses tumor ang ...... a stabilization under hypoxia.
@nl
prefLabel
Melatonin suppresses tumor ang ...... a stabilization under hypoxia.
@en
Melatonin suppresses tumor ang ...... a stabilization under hypoxia.
@nl
P2093
P1476
Melatonin suppresses tumor ang ...... a stabilization under hypoxia.
@en
P2093
Eui-Yeun Yi
Ji-Yeong Jang
Joo-Won Jeong
Shi-Young Park
Won-Jun Jang
Yung-Jin Kim
Yunjin Jung
P2860
P304
P356
10.1111/J.1600-079X.2009.00742.X
P577
2010-03-01T00:00:00Z