Protein modification, bioconjugation, and disulfide bridging using bromomaleimides. - Wikidata - wikimedia - TriplyDB

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

http://www.wikidata.org/entity/Q39707456

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Cys34-PEGylated Human Serum Albumin for Drug Binding and Delivery Choosing an effective protein bioconjugation strategy Diverse functionalization of Aurora-A kinase at specified surface and buried sites by native chemical modification Grafting synthetic transmembrane units to the engineered low-toxicity α-hemolysin to restore its hemolytic activity.Smart hybrid materials by conjugation of responsive polymers to biomacromolecules.Degradable conjugates from oxanorbornadiene reagents RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.New method for effectively and quantitatively labeling cysteine residues on chicken eggshell membrane.Emerging synthetic approaches for protein-polymer conjugations N-terminal modification of proteins with o-aminophenols.Tunable degradation of maleimide-thiol adducts in reducing environments Click chemistry patents and their impact on drug discovery and chemical biology.Homogeneous bispecifics by disulfide bridging.Reduction-responsive dithiomaleimide-based nanomedicine with high drug loading and FRET-indicated drug release Bromomaleimide-linked bioconjugates are cleavable in mammalian cells Aminomaleimide fluorophores: a simple functional group with bright, solvent dependent emission.Oxidation Protection in Metal-Binding Peptide Motif and Its Application to Antibody for Site-Selective Conjugation.Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.Facile and stabile linkages through tyrosine: bioconjugation strategies with the tyrosine-click reaction.Field Guide to Challenges and Opportunities in Antibody-Drug Conjugates for Chemists.Molecular scaffolds using multiple orthogonal conjugations: applications in chemical biology and drug discovery.Selective chemical protein modification.Rational design of reversible and irreversible cysteine sulfenic acid-targeted linear C-nucleophiles.Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.Fluorescent-labeled bioconjugates of the opioid peptides biphalin and DPDPE incorporating fluorescein-maleimide linkers.Chemical Protein Modification through Cysteine.Towards the next generation of biomedicines by site-selective conjugation.A novel approach to the site-selective dual labelling of a protein via chemoselective cysteine modification.Nanostructure formation-induced fluorescence turn-on for selectively detecting protein thiols in solutions, bacteria and live cells.A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy.Site-Selective Disulfide Modification of Proteins: Expanding Diversity beyond the Proteome.Peptide/protein stapling and unstapling: introduction of s-tetrazine, photochemical release, and regeneration of the peptide/protein.In situ maleimide bridging of disulfides and a new approach to protein PEGylation.Controlling topological entanglement in engineered protein hydrogels with a variety of thiol coupling chemistries.Dual Functionalized Bacteriophage Qβ as a Photocaged Drug Carrier.Site-specific conjugation of RAFT polymers to proteins via expressed protein ligation Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation Bioconjugation of green fluorescent protein via an unexpectedly stable cyclic sulfonium intermediate.

P2860

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P2860

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

http://www.wikidata.org/entity/Q39707456

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

2010年學術文章

@zh

2010年學術文章

@zh-hant

name

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

@en

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

@nl

type

label

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

@en

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

@nl

prefLabel

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

@en

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

@nl

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Journal of the American Chemical Society

P1476

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

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P2093

Chris P Ryan

http://www.w3.org/2001/XMLSchema#string

Danai Papaioannou

http://www.w3.org/2001/XMLSchema#string

Felix F Schumacher

http://www.w3.org/2001/XMLSchema#string

Gabriel Waksman

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James R Baker

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Lauren M Tedaldi

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Mark E B Smith

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Stephen Caddick

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P2860

Occurrence, conformational features and amino acid propensities for the pi-helix

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

Site-specific PEGylation of protein disulfide bonds using a three-carbon bridge.

Somatostatin analogs in acromegaly.

Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities.

Disulfide bridge based PEGylation of proteins.

Chemical modification of proteins at cysteine: opportunities in chemistry and biology.

Somatostatin analog octreotide LAR in gastro-entero-pancreatic tumors.

Synthesis and characterization of novel thiol-reactive poly(ethylene glycol) cross-linkers for extracellular-matrix-mimetic biomaterials.

Site-specific PEGylation of native disulfide bonds in therapeutic proteins.

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41110440

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20092331

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2842020

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