The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production
about
Progress and problems in understanding and managing primary Epstein-Barr virus infectionsPosttransplant lymphoproliferative disease after pediatric solid organ transplantationRegulation of the latent-lytic switch in Epstein-Barr virusCurrent and potential treatments for ubiquitous but neglected herpesvirus infectionsIdentification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial MalignanciesPhosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic SignalingArsenic trioxide inhibits EBV reactivation and promotes cell death in EBV-positive lymphoma cells.Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.Zidovudine-based lytic-inducing chemotherapy for Epstein-Barr virus-related lymphomas.Cellular microRNAs 200b and 429 regulate the Epstein-Barr virus switch between latency and lytic replication.Spironolactone blocks Epstein-Barr virus production by inhibiting EBV SM protein function.Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication.Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agentsTargeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation.LMP1-Induced Sumoylation Influences the Maintenance of Epstein-Barr Virus Latency through KAP1Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virusKey motifs in EBV (Epstein-Barr virus)-encoded protein kinase for phosphorylation activity and nuclear localization.Application of a patient-derived xenograft model in cytolytic viral activation therapy for nasopharyngeal carcinomaEpstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profileActivity and mechanism of action of HDVD, a novel pyrimidine nucleoside derivative with high levels of selectivity and potency against gammaherpesvirusesAtypical Epstein-Barr viral genomic structure in lymphoma tissue and lymphoid cell linesHsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cellsDevelopment of drugs for Epstein-Barr virus using high-throughput in silico virtual screeningInteractome mapping: using protein microarray technology to reconstruct diverse protein networks.Epstein-Barr viral productive amplification reprograms nuclear architecture, DNA replication, and histone deposition.Viral serine/threonine protein kinasesLenalidomide, Thalidomide, and Pomalidomide Reactivate the Epstein-Barr Virus Lytic Cycle through Phosphoinositide 3-Kinase Signaling and Ikaros Expression.Zinc finger E-box binding factor 1 plays a central role in regulating Epstein-Barr virus (EBV) latent-lytic switch and acts as a therapeutic target in EBV-associated gastric cancer.Arsenic mediated disruption of promyelocytic leukemia protein nuclear bodies induces ganciclovir susceptibility in Epstein-Barr positive epithelial cells.Simian virus 40 T/t antigens and lamin A/C small interfering RNA rescue the phenotype of an Epstein-Barr virus protein kinase (BGLF4) mutant.The duck enteritis virus early protein, UL13, found in both nucleus and cytoplasm, influences viral replication in cell culture.Gastric adenocarcinoma microRNA profiles in fixed tissue and in plasma reveal cancer-associated and Epstein-Barr virus-related expression patterns.Co-treatment with arsenic trioxide and ganciclovir reduces tumor volume in a murine xenograft model of nasopharyngeal carcinoma.Three Molecular Subtypes of Gastric Adenocarcinoma Have Distinct Histochemical Features Reflecting Epstein-Barr Virus Infection Status and Neuroendocrine Differentiation.Spectrum of activity and mechanisms of resistance of various nucleoside derivatives against gammaherpesviruses.SUMO binding by the Epstein-Barr virus protein kinase BGLF4 is crucial for BGLF4 function.In vivo intratumoral Epstein-Barr virus replication is associated with XBP1 activation and early-onset post-transplant lymphoproliferative disorders with prognostic implications.Characteristics of Epstein-Barr viraemia in adult liver transplant patients: a retrospective cohort study.B Cell Receptor Activation and Chemical Induction Trigger Caspase-Mediated Cleavage of PIAS1 to Facilitate Epstein-Barr Virus Reactivation.Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk).
P2860
Q24597706-2ED886CE-CBE4-4969-ABDE-7504702997C9Q26866013-B289DA34-A5B6-4175-A55E-41E6F306645AQ27021366-D37ED789-7E04-4BBF-A479-625D96741797Q27023452-DD790A41-906F-4C1D-A33D-B723E0C42769Q28551855-F89781DE-B12D-492D-B224-00E521469339Q28551996-3A49FF0A-99C8-467F-8E5A-68BDFCF762BEQ33823359-AD4FF20E-B807-44DC-A9AE-E6B7013BB6F0Q33842381-8D9EEEFB-6A38-43CB-A209-9674CCC809DBQ34053519-D32A442B-6CA2-4511-8429-B29E078EBE0DQ34120915-6F7681B7-8852-4162-A759-0258414A12AAQ34518160-BFE2A858-4981-483F-A0B4-091929F7B5D9Q35660314-D5A699B9-8164-49E2-BB82-281C64C4A1D0Q35733719-2A8ADE61-42CD-4D0B-8C1D-E4CE957CBCCAQ35795380-088DA434-9A77-4097-AFF9-ACDC4C65D378Q35861199-9B1CC466-FA78-4313-9DC9-3837D7705DC6Q36346985-27994D90-F07A-412A-BFED-D3BA360E9278Q36399836-CA3BD55A-519C-4330-A796-233236B08358Q36544568-F1DE40D4-1BC7-4877-84A3-2BBA48FB302AQ36687528-62029920-E2DD-45F6-B761-4ED22006C678Q36759709-C7F25594-3FF7-4C4A-B955-02973DFF6905Q36847178-CE5D0BA0-C52D-4861-A45D-2CBCE288DE1BQ37123188-AE7514F3-AEF0-43DC-BDE2-7436FC231B5AQ37278489-9DD9CDEC-4ABD-4F3C-AF5E-BBB278A82DBAQ37671058-7FACF1AD-3199-4A47-B59C-A5DEB6BAC962Q37716502-CB75F77D-36FE-4DA7-B863-92BB59188D0FQ37810382-44C05079-EB4D-4215-81C1-2F4E4F3AA52CQ38379791-D1A42BF6-A68D-452D-BC28-7CDA23025467Q39515516-56745BF3-0202-4A61-8B2C-1F39546F36EBQ39537817-61380696-3EA0-42D9-8953-F1670D305F88Q39741182-CAD34724-06BE-4A27-9DCD-ACE3DB9DE8D9Q40260637-36542A75-97B9-4F0D-B726-7A1744722A6EQ40764983-6A567E26-6003-46C0-8BF8-A49CD5E00EC4Q41165122-745886D0-CF82-485F-B0F9-BD934021F206Q41594529-9853BBB9-DA9E-40A0-9962-FDBF1E894B12Q41722018-698B2D73-CF84-416E-A420-92CE349D07F2Q41983297-E2A8EB82-DAD3-4D3B-B478-B8CF2FCF8FB3Q42222507-AD8A9783-5390-4ABF-80C3-6A399F9858B4Q42223339-AD3CBFF0-0843-46B6-AD6C-237F5D2E323CQ47137780-D34957C6-878C-45A9-8687-1A031778AB47Q47319898-10A9862B-1498-4DE5-8CDC-EA8594E013D4
P2860
The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
The Epstein-Barr virus (EBV)-e ...... tion of lytic viral production
@en
The Epstein-Barr virus (EBV)-e ...... ion of lytic viral production.
@nl
type
label
The Epstein-Barr virus (EBV)-e ...... tion of lytic viral production
@en
The Epstein-Barr virus (EBV)-e ...... ion of lytic viral production.
@nl
prefLabel
The Epstein-Barr virus (EBV)-e ...... tion of lytic viral production
@en
The Epstein-Barr virus (EBV)-e ...... ion of lytic viral production.
@nl
P2093
P2860
P356
P1433
P1476
The Epstein-Barr virus (EBV)-e ...... tion of lytic viral production
@en
P2093
Joseph S Pagano
Joyce D Fingeroth
Shannon C Kenney
Stacy R Hagemeier
P2860
P304
P356
10.1128/JVI.02487-09
P407
P577
2010-02-24T00:00:00Z