Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. - Wikidata - wikimedia - TriplyDB

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells.

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells.

http://www.wikidata.org/entity/Q39740070

about

Angiogenic factors stimulate growth of adult neural stem cells Angiopoietin-1 is essential in mouse vasculature during development and in response to injury.Targeting neural precursors in the adult brain rescues injured dopamine neurons The role of pericytes in blood-vessel formation and maintenance Neonatal brain hemorrhage (NBH) of prematurity: translational mechanisms of the vascular-neural network The role of sphingosine-1-phosphate in endothelial barrier function Engineering of in vitro 3D capillary beds by self-directed angiogenic sprouting Mural cell associated VEGF is required for organotypic vessel formation Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown Fit for the Eye: Aptamers in Ocular Disorders Intravitreal AAV2.COMP-Ang1 Prevents Neurovascular Degeneration in a Murine Model of Diabetic Retinopathy.Identification of novel drug targets for the treatment of diabetic retinopathy.Embryonic lung side population cells are hematopoietic and vascular precursors.Microvascular engineering in perfusion culture: immunohistochemistry and CLSM findings Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy.Molecular mediators of angiogenesis.Plastic roles of pericytes in the blood-retinal barrier.Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF.COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis Rescuing vasculature with intravenous angiopoietin-1 and alpha v beta 3 integrin peptide is protective after spinal cord injury.Multimodality imaging of abnormal vascular perfusion and morphology in preclinical 9L gliosarcoma model Stimulation of in vivo angiogenesis by in situ crosslinked, dual growth factor-loaded, glycosaminoglycan hydrogels.The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability.Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes Angiogenesis and vascular malformations: antiangiogenic drugs for treatment of gastrointestinal bleeding.Vascular smooth muscle Notch signals regulate endothelial cell sensitivity to angiogenic stimulation.Targeting microvasculature for neuroprotection after SCI Rapid vascular regrowth in tumors after reversal of VEGF inhibition.Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization.Egfl7 is differentially expressed in arteries and veins during retinal vascular development.Stimulation of in vivo angiogenesis using dual growth factor-loaded crosslinked glycosaminoglycan hydrogels.Controlled protein delivery in the generation of microvascular networks.Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade Type I collagen, fibrin and PuraMatrix matrices provide permissive environments for human endothelial and mesenchymal progenitor cells to form neovascular networks Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma.

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P2860

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells.

http://www.wikidata.org/entity/Q39740070

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Recombinant angiopoietin-1 res ...... in the absence of mural cells.

@en

Recombinant angiopoietin-1 res ...... in the absence of mural cells.

@nl

type

label

Recombinant angiopoietin-1 res ...... in the absence of mural cells.

@en

Recombinant angiopoietin-1 res ...... in the absence of mural cells.

@nl

prefLabel

Recombinant angiopoietin-1 res ...... in the absence of mural cells.

@en

Recombinant angiopoietin-1 res ...... in the absence of mural cells.

@nl

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P1433

Journal of Clinical Investigation

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Recombinant angiopoietin-1 res ...... in the absence of mural cells

@en

P2093

George D Yancopoulos

http://www.w3.org/2001/XMLSchema#string

Hitoshi Takagi

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Masanori Hirashima

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Minetaro Ogawa

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Shin-Ichi Nishikawa

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Shinji Koyama

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Stanley J Wiegand

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Takashi Fujiwara

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Yoshihito Honda

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P2860

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis

Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity

Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function

Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis

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1619-1628

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10.1172/JCI0215621

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11

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110

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Akiyoshi Uemura

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12464667

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151628

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