The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
about
Defining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermathCytoskeleton in motion: the dynamics of keratin intermediate filaments in epitheliaPost-translational modifications of intermediate filament proteins: mechanisms and functionsA Drosophila Model of Epidermolysis Bullosa Simplex.Multiple roles for keratin intermediate filaments in the regulation of epithelial barrier function and apico-basal polarityA Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promiseStabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragilityKeratin gene mutations in disorders of human skin and its appendages.Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfideE3 ubiquitin ligases in protein quality control mechanism.Keratins and disease at a glance.Gene expression analysis of an epidermolysis bullosa simplex Dowling-Meara cell line by subtractive hybridization: recapitulation of cellular differentiation, migration and wound healing.Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a useful in vitro model for testing new treatments.Novel origin of lamin-derived cytoplasmic intermediate filaments in tardigrades.E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients."Panta rhei": Perpetual cycling of the keratin cytoskeleton.
P2860
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P2860
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
@zh-hant
name
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
@en
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
@nl
type
label
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
@en
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
@nl
prefLabel
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
@en
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
@nl
P2093
P356
P1433
P1476
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation
@en
P2093
Cristina Has
Jörg Höhfeld
Stefan Wöll
Stefanie Löffek
Thomas M Magin
P304
P356
10.1002/HUMU.21222
P577
2010-04-01T00:00:00Z