Cytokine-armed vaccinia virus infects the mesothelioma tumor microenvironment to overcome immune tolerance and mediate tumor resolution.
about
The "Trojan Horse" approach to tumor immunotherapy: targeting the tumor microenvironment.Murine mesothelioma induces locally-proliferating IL-10(+)TNF-α(+)CD206(-)CX3CR1(+) M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy.Cytokines in cancer immunotherapy.IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice.Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice.Intratumoral interleukin-2/agonist CD40 antibody drives CD4+ -independent resolution of treated-tumors and CD4+ -dependent systemic and memory responses.Recombinant Poxvirus and the Tumor Microenvironment: Oncolysis, Immune Regulation and Immunization.Tune Up In Situ Autovaccination against Solid Tumors with Oncolytic Viruses.
P2860
Q33736218-5F361C51-FDB3-4F23-9147-614F32739789Q37078960-E3DA65A0-24B4-4625-AB52-FA63F3B3E33BQ37148152-7B51720E-C78B-45BB-8CAC-653FB0400B87Q39003110-5C5A3128-EA1A-4372-B1F6-830CCBF04BDBQ39188424-8D428429-7B13-4774-8919-F937A2C9F6D5Q39457393-45ECF42B-C335-4500-BB41-77064ED06F8CQ51007512-AF6A831A-F5F0-4F2A-9EFE-740B8A6E43EEQ55509278-209FB554-0A38-4882-A544-0A261A2AA3E4
P2860
Cytokine-armed vaccinia virus infects the mesothelioma tumor microenvironment to overcome immune tolerance and mediate tumor resolution.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Cytokine-armed vaccinia virus ...... and mediate tumor resolution.
@en
Cytokine-armed vaccinia virus ...... and mediate tumor resolution.
@nl
type
label
Cytokine-armed vaccinia virus ...... and mediate tumor resolution.
@en
Cytokine-armed vaccinia virus ...... and mediate tumor resolution.
@nl
prefLabel
Cytokine-armed vaccinia virus ...... and mediate tumor resolution.
@en
Cytokine-armed vaccinia virus ...... and mediate tumor resolution.
@nl
P2860
P356
P1433
P1476
Cytokine-armed vaccinia virus ...... and mediate tumor resolution.
@en
P2093
C Jackaman
D J Nelson
P2860
P2888
P304
P356
10.1038/CGT.2009.85
P577
2010-02-12T00:00:00Z
P5875
P6179
1022036783