Reovirus sigma NS protein localizes to inclusions through an association requiring the mu NS amino terminus.
about
The mammalian orthoreovirus bicistronic M3 mRNA initiates translation using a 5' end-dependent, scanning mechanism that does not require interaction of 5'-3' untranslated regionsGene-specific inhibition of reovirus replication by RNA interference.Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking.Localization of mammalian orthoreovirus proteins to cytoplasmic factory-like structures via nonoverlapping regions of microNSTurbot reovirus (SMReV) genome encoding a FAST protein with a non-AUG start siteVirus-mediated compartmentalization of the host translational machinery.Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1.Aquareovirus NS80 recruits viral proteins to its inclusions, and its C-terminal domain is the primary driving force for viral inclusion formation.Nonstructural protein NS80 is crucial in recruiting viral components to form aquareoviral factories.Sequence analysis of the genome of piscine orthoreovirus (PRV) associated with heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar).Functional investigation of grass carp reovirus nonstructural protein NS80.Aquareovirus NS80 Initiates Efficient Viral Replication by Retaining Core Proteins within Replication-Associated Viral Inclusion Bodies.Guanidine hydrochloride inhibits mammalian orthoreovirus growth by reversibly blocking the synthesis of double-stranded RNA.Characterization of grass carp reovirus minor core protein VP4.Reovirus uses multiple endocytic pathways for cell entry.Identification of functional domains in reovirus replication proteins muNS and mu2.Sequences of avian reovirus M1, M2 and M3 genes and predicted structure/function of the encoded mu proteins.Reovirus forms neo-organelles for progeny particle assembly within reorganized cell membranes.An ITAM in a nonenveloped virus regulates activation of NF-κB, induction of beta interferon, and viral spread.Identification and characterization of two cleavage fragments from the Aquareovirus nonstructural protein NS80.Amino acids 78 and 79 of Mammalian Orthoreovirus protein µNS are necessary for stress granule localization, core protein λ2 interaction, and de novo virus replication.Reovirus replication protein μ2 influences cell tropism by promoting particle assembly within viral inclusions.The cellular chaperone hsc70 is specifically recruited to reovirus viral factories independently of its chaperone function.Increased ubiquitination and other covariant phenotypes attributed to a strain- and temperature-dependent defect of reovirus core protein mu2.Formation of the factory matrix is an important, though not a sufficient function of nonstructural protein mu NS during reovirus infection.Reovirus inhibits interferon production by sequestering IRF3 into viral factories.Characterization of a replicating mammalian orthoreovirus with tetracysteine tagged μNS for live cell visualization of viral factories.Mammalian Orthoreovirus Factories Modulate Stress Granule Protein Localization by Interaction with G3BP1.Silencing and complementation of reovirus core protein mu2: functional correlations with mu2-microtubule association and differences between virus- and plasmid-derived mu2.Avian reovirus microNS protein forms homo-oligomeric inclusions in a microtubule-independent fashion, which involves specific regions of its C-terminal domainCarboxyl-proximal regions of reovirus nonstructural protein muNS necessary and sufficient for forming factory-like inclusions.Reovirus nonstructural protein mu NS recruits viral core surface proteins and entering core particles to factory-like inclusions.Mammalian orthoreovirus particles induce and are recruited into stress granules at early times postinfectionA plasmid-based reverse genetics system for animal double-stranded RNA viruses.Virus-derived platforms for visualizing protein associations inside cells.Non-structural protein σ1s is required for optimal reovirus protein expression.Reovirus Nonstructural Protein σNS Acts as an RNA-Stability Factor Promoting Viral Genome Replication.Reovirus σNS and μNS Proteins Remodel the Endoplasmic Reticulum to Build Replication Neo-Organelles
P2860
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P2860
Reovirus sigma NS protein localizes to inclusions through an association requiring the mu NS amino terminus.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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name
Reovirus sigma NS protein loca ...... ring the mu NS amino terminus.
@en
Reovirus sigma NS protein loca ...... ring the mu NS amino terminus.
@nl
type
label
Reovirus sigma NS protein loca ...... ring the mu NS amino terminus.
@en
Reovirus sigma NS protein loca ...... ring the mu NS amino terminus.
@nl
prefLabel
Reovirus sigma NS protein loca ...... ring the mu NS amino terminus.
@en
Reovirus sigma NS protein loca ...... ring the mu NS amino terminus.
@nl
P2093
P2860
P1433
P1476
Reovirus sigma NS protein loca ...... ring the mu NS amino terminus.
@en
P2093
John S L Parker
Max L Nibert
Michelle M Arnold
Teresa J Broering
P2860
P304
P356
10.1128/JVI.77.8.4566-4576.2003
P407
P577
2003-04-01T00:00:00Z