CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. - Wikidata - wikimedia - TriplyDB

CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

http://www.wikidata.org/entity/Q39744964

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Treatment with disease modifying drugs for people with a first clinical attack suggestive of multiple sclerosis Immunomodulators and immunosuppressants for relapsing-remitting multiple sclerosis: a network meta-analysis Immunomodulators and immunosuppressants for relapsing-remitting multiple sclerosis: a network meta-analysis Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis Azathioprine for multiple sclerosis Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease A review of the medical treatment of primary sclerosing cholangitis in the 21st century Chronic Renal Transplant Rejection and Possible Anti-Proliferative Drug Targets Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?Review article: the management of autoimmune hepatitis beyond consensus guidelines Systematic review: macrophage activation syndrome in inflammatory bowel disease T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue.Inflammatory Bowel Disease Drugs: A Focus on Autophagy Rac Attack: Modulation of the Small GTPase Rac in Inflammatory Bowel Disease and Thiopurine Therapy Thiopurines and inflammatory bowel disease: Current evidence and a historical perspective Reconsidering the detection of tolerance to individualize immunosuppression minimization and to improve long-term kidney graft outcomes Optimizing the use of thiopurines in inflammatory bowel disease Pharmacogenetics in inflammatory bowel disease Gene expression and thiopurine metabolite profiling in inflammatory bowel disease - novel clues to drug targets and disease mechanisms?Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients Treatment with disease-modifying drugs for people with a first clinical attack suggestive of multiple sclerosis.Diminished macrophage apoptosis and reactive oxygen species generation after phorbol ester stimulation in Crohn's disease.Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines.Long term efficacy and safety of allopurinol and azathioprine or 6-mercaptopurine in patients with inflammatory bowel disease.6-methylmercaptopurine-induced leukocytopenia during thiopurine therapy in inflammatory bowel disease patients.Comprehensive characterization of (S)GTP-binding proteins by orthogonal quantitative (S)GTP-affinity profiling and (S)GTP/GTP competition assays.Use of thiopurines in inflammatory bowel disease: Safety issues.A network-based kernel machine test for the identification of risk pathways in genome-wide association studies Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression Profiles Relationship between Azathioprine metabolites and therapeutic efficacy in Chinese patients with neuromyelitis optica spectrum disorders Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis.LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine Update on the risk of lymphoma following immunosuppressive therapy for inflammatory bowel disease.Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy.Normal response to vaccines in inflammatory bowel disease patients treated with thiopurines Azathioprine: old drug, new actions.Purine analogues compared with mesalamine or 5-ASA for the prevention of postoperative recurrence in Crohn's disease: a meta-analysis.Pharmacogenetics of azathioprine in inflammatory bowel disease: a role for glutathione-S-transferase?

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P2860

CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

http://www.wikidata.org/entity/Q39744964

description

2003 nî lūn-bûn

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

CD28-dependent Rac1 activation ...... mary human CD4+ T lymphocytes.

@en

CD28-dependent Rac1 activation ...... mary human CD4+ T lymphocytes.

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type

label

CD28-dependent Rac1 activation ...... mary human CD4+ T lymphocytes.

@en

CD28-dependent Rac1 activation ...... mary human CD4+ T lymphocytes.

@nl

prefLabel

CD28-dependent Rac1 activation ...... mary human CD4+ T lymphocytes.

@en

CD28-dependent Rac1 activation ...... mary human CD4+ T lymphocytes.

@nl

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Journal of Clinical Investigation

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CD28-dependent Rac1 activation ...... mary human CD4+ T lymphocytes.

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P2093

Brigitte Bartsch

http://www.w3.org/2001/XMLSchema#string

Christoph Becker

http://www.w3.org/2001/XMLSchema#string

Daniela Poppe

http://www.w3.org/2001/XMLSchema#string

Dennis Strand

http://www.w3.org/2001/XMLSchema#string

Gerhard Fritz

http://www.w3.org/2001/XMLSchema#string

Hans Anton Lehr

http://www.w3.org/2001/XMLSchema#string

Heiko Iven

http://www.w3.org/2001/XMLSchema#string

Henning Walczak

http://www.w3.org/2001/XMLSchema#string

Imke Tiede

http://www.w3.org/2001/XMLSchema#string

Jonas Mudter

http://www.w3.org/2001/XMLSchema#string

P2860

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Regulation of STAT3 by direct binding to the Rac1 GTPase

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

Long-term azathioprine in rheumatoid arthritis: a double-blind study.

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment.

Apoptosis signaling in lymphocytes.

Recent developments in the immunology of inflammatory bowel disease.

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1133-1145

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10.1172/JCI16432

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8

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111

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12697733

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152932

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