Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy.
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Research Progress on the Role of ABC Transporters in the Drug Resistance Mechanism of Intractable EpilepsyEffects of sertraline and fluoxetine on p-glycoprotein at barrier sites: in vivo and in vitro approachesA multi-system approach assessing the interaction of anticonvulsants with P-gpValerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish)Drug-Resistant Epilepsy: Multiple Hypotheses, Few AnswersEffect of transporter inhibition on the distribution of cefadroxil in rat brainTargeting the neurovascular unit for treatment of neurological disorders.The impact of the use of antiepileptic drugs on the growth of childrenDrug resistance in cortical and hippocampal slices from resected tissue of epilepsy patients: no significant impact of p-glycoprotein and multidrug resistance-associated proteinsPharmGKB summary: phenytoin pathway.Influence of enterohepatic recycling on the time course of brain-to-blood partitioning of valproic acid in rats.Significance of the expression of MRP1 and MRP2 in peripheral blood mononuclear cells of children with intractable epilepsy.Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy.(R)-[(11)C]verapamil is selectively transported by murine and human P-glycoprotein at the blood-brain barrier, and not by MRP1 and BCRP.RLIP76 Gene Variants are not Associated with Drug Response in Turkish Epilepsy Patients.The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study.Development of purine-derived 18F-labeled pro-drug tracers for imaging of MRP1 activity with PET.Transporter hypothesis of drug-resistant epilepsy: challenges for pharmacogenetic approaches.Epilepsy in patients with a brain tumour: focal epilepsy requires focused treatment.A systematic review and meta-analysis of the role of ABCC2 variants on drug response in patients with epilepsy.Effect of Disease Pathologies on Transporter Expression and Function.Multidrug resistance-associated protein 1 decreases the concentrations of antiepileptic drugs in cortical extracellular fluid in amygdale kindling rats.Effect of Oxidative Stress on ABC Transporters: Contribution to Epilepsy Pharmacoresistance.Quantitative fluorescence microscopy provides high resolution imaging of passive diffusion and P-gp mediated efflux at the in vivo blood-brain barrier.Influence of single-nucleotide polymorphisms on deferasirox C trough levels and effectiveness.Computational and Pharmacological Target of Neurovascular Unit for Drug Design and Delivery.PharmGKB summary: carbamazepine pathway.Overexpression of human MRP1 in neurons causes resistance to antiepileptic drugs in Drosophila seizure mutants.ABCC2 rs2273697 and rs3740066 polymorphisms and resistance to antiepileptic drugs in Asia Pacific epilepsy cohorts.Altered Function and Expression of ABC Transporters at the Blood-Brain Barrier and Increased Brain Distribution of Phenobarbital in Acute Liver Failure Mice.A comprehensive functional and clinical analysis of ABCC2 and its impact on treatment response to carbamazepine
P2860
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P2860
Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Evaluation of transport of com ...... in pharmacoresistant epilepsy.
@en
Evaluation of transport of com ...... in pharmacoresistant epilepsy.
@nl
type
label
Evaluation of transport of com ...... in pharmacoresistant epilepsy.
@en
Evaluation of transport of com ...... in pharmacoresistant epilepsy.
@nl
prefLabel
Evaluation of transport of com ...... in pharmacoresistant epilepsy.
@en
Evaluation of transport of com ...... in pharmacoresistant epilepsy.
@nl
P2093
P1433
P1476
Evaluation of transport of com ...... in pharmacoresistant epilepsy.
@en
P2093
Carlos Luna-Tortós
Maren Fedrowitz
Wolfgang Löscher
P304
P356
10.1016/J.NEUROPHARM.2010.01.007
P577
2010-01-18T00:00:00Z