The Cdk5 kinase downregulates ATP-gated ionotropic P2X3 receptor function via serine phosphorylation.
about
Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal painRegulation of ATP-gated P2X channels: from redox signaling to interactions with other proteinsB-type natriuretic peptide-induced delayed modulation of TRPV1 and P2X3 receptors of mouse trigeminal sensory neurons.Activation and regulation of purinergic P2X receptor channelsAllosteric modulation of ATP-gated P2X receptor channelsTargeted overexpression of tumor necrosis factor-α increases cyclin-dependent kinase 5 activity and TRPV1-dependent Ca2+ influx in trigeminal neuronsActivation of cyclin-dependent kinase 5 mediates orofacial mechanical hyperalgesia.ATP P2X3 receptors and neuronal sensitization.Cdk5: An Emerging Kinase in Pain SignalingBrain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localizationP2X3 receptor expression by HEK cells conditions their survival.Mutated CaV2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice.Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine.Calcium/calmodulin-dependent serine protein kinase (CASK) is a new intracellular modulator of P2X3 receptors.Modulation of TRPA1 channel activity by Cdk5 in Sensory neurons.Cyclin-dependent kinase 5 modulates the P2X2a receptor channel gating through phosphorylation of C-terminal threonine 372.P2X3 receptor: a novel 'CASKade' of signaling?Sigmoid colon mucosal gene expression supports alterations of neuronal signaling in irritable bowel syndrome with constipation.
P2860
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P2860
The Cdk5 kinase downregulates ATP-gated ionotropic P2X3 receptor function via serine phosphorylation.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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name
The Cdk5 kinase downregulates ...... on via serine phosphorylation.
@en
The Cdk5 kinase downregulates ...... on via serine phosphorylation.
@nl
type
label
The Cdk5 kinase downregulates ...... on via serine phosphorylation.
@en
The Cdk5 kinase downregulates ...... on via serine phosphorylation.
@nl
prefLabel
The Cdk5 kinase downregulates ...... on via serine phosphorylation.
@en
The Cdk5 kinase downregulates ...... on via serine phosphorylation.
@nl
P2093
P1476
The Cdk5 kinase downregulates ...... on via serine phosphorylation.
@en
P2093
Andrea Nistri
Elsa Fabbretti
Manuela Simonetti
P2888
P304
P356
10.1007/S10571-009-9483-2
P577
2009-12-04T00:00:00Z