Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing
about
Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo.Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing.Recent progress in nanomaterials for gene delivery applications.Engineered Hydrogels for Local and Sustained Delivery of RNA-Interference Therapies.Anionic Polymer and Quantum Dot Excipients to Facilitate siRNA Release and Self-Reporting of Disassembly in Stimuli-Responsive Nanocarrier Formulations.
P2860
Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Hydrophobic interactions betwe ...... etics and tumor gene silencing
@en
Hydrophobic interactions betwe ...... tics and tumor gene silencing.
@nl
type
label
Hydrophobic interactions betwe ...... etics and tumor gene silencing
@en
Hydrophobic interactions betwe ...... tics and tumor gene silencing.
@nl
prefLabel
Hydrophobic interactions betwe ...... etics and tumor gene silencing
@en
Hydrophobic interactions betwe ...... tics and tumor gene silencing.
@nl
P2093
P2860
P1433
P1476
Hydrophobic interactions betwe ...... etics and tumor gene silencing
@en
P2093
Craig L Duvall
Irene Chandra
Madison E Hattaway
Meredith A Jackson
Samantha M Sarett
Taylor E Kavanaugh
Thomas A Werfel
Todd D Giorgio
P2860
P304
P356
10.1016/J.BIOMATERIALS.2016.04.017
P577
2016-04-21T00:00:00Z