Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells.
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Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motifChanges in the quaternary structure and function of MjHSP16.5 attributable to deletion of the IXI motif and introduction of the substitution, R107G, in the -crystallin domainThe specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability.Role of alphaBI5 and alphaBT162 residues in subunit interaction during oligomerization of alphaB-crystallin.Age-related changes in the spatial distribution of human lens alpha-crystallin products by MALDI imaging mass spectrometry.Cataract-causing αAG98R-crystallin mutant dissociates into monomers having chaperone activity.Multiple sites in αB-crystallin modulate its interactions with desmin filaments assembled in vitro.Functional validation of hydrophobic adaptation to physiological temperature in the small heat shock protein αA-crystallinSelective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathwaysPhysiological expression of lens α-, β-, and γ-crystallins in murine and human corneas.Different alpha crystallin expression in human age-related and congenital cataract lens epithelium.Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress.alphaB-crystallin: a hybrid solid-state/solution-state NMR investigation reveals structural aspects of the heterogeneous oligomer.Lens aging: effects of crystallins.Functions of the intermediate filament cytoskeleton in the eye lens.Barcoding heat shock proteins to human diseases: looking beyond the heat shock responseSmall heat-shock proteins: important players in regulating cellular proteostasis.Truncation attenuates molecular chaperoning and apoptosis inhibition by p26, a small heat shock protein from Artemia franciscana.C-terminal interactions mediate the quaternary dynamics of αB-crystallin.Oligomerization with wt αA- and αB-crystallins reduces proteasome-mediated degradation of C-terminally truncated αA-crystallin.The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity.The role of the cysteine residue in the chaperone and anti-apoptotic functions of human Hsp27.The Function of Ile-X-Ile Motif in the Oligomerization and Chaperone-Like Activity of Small Heat Shock Protein AgsA at Room Temperature.The functional roles of the unstructured N- and C-terminal regions in αB-crystallin and other mammalian small heat-shock proteins.
P2860
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P2860
Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
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2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
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2008年论文
@zh-cn
name
Truncation of alphaB-crystalli ...... ormation in transfected cells.
@en
Truncation of alphaB-crystalli ...... ormation in transfected cells.
@nl
type
label
Truncation of alphaB-crystalli ...... ormation in transfected cells.
@en
Truncation of alphaB-crystalli ...... ormation in transfected cells.
@nl
prefLabel
Truncation of alphaB-crystalli ...... ormation in transfected cells.
@en
Truncation of alphaB-crystalli ...... ormation in transfected cells.
@nl
P2093
P2860
P356
P1476
Truncation of alphaB-crystalli ...... ormation in transfected cells.
@en
P2093
Glyn Devlin
Roy A Quinlan
Victoria H Hayes
P2860
P304
10500-10512
P356
10.1074/JBC.M706453200
P407
P577
2008-01-29T00:00:00Z