Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads. - Wikidata - wikimedia - TriplyDB

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads.

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads.

http://www.wikidata.org/entity/Q39791091

about

Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1 Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation Cathespin H is an Fgf10 target involved in Bmp4 degradation during lung branching morphogenesis Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6 Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7 The ubiquitin proteasome system in neuropathology Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA Key role for ubiquitin protein modification in TGFβ signal transduction Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy A novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedback Ubiquitination of RhoA by Smurf1 promotes neurite outgrowth Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)OAZ regulates bone morphogenetic protein signaling through Smad6 activation Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells Methylation of Smad6 by protein arginine N-methyltransferase 1 Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation HECT E3s and human disease.Muscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition.Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad.MiR-503 Promotes Bone Formation in Distraction Osteogenesis through Suppressing Smurf1 Expression Smad signaling in skeletal development and regeneration.A positive role of microRNA-15b on regulation of osteoblast differentiation.USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.Regulated Entry of Hepatitis C Virus into Hepatocytes.Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor.Proteomic analysis of sera of asymptomatic, early-stage patients with Wilson's disease.Bone morphogenetic proteins and their antagonists: current and emerging clinical uses.LIM mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads.The amiloride derivative phenamil attenuates pulmonary vascular remodeling by activating NFAT and the bone morphogenetic protein signaling pathway.Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints Burst BMP triggered receptor kinase activity drives Smad1 mediated long-term target gene oscillation in C2C12 cells SMURF1 silencing diminishes a CD44-high cancer stem cell-like population in head and neck squamous cell carcinoma.Smad7 regulates terminal maturation of chondrocytes in the growth plate Ubiquitin-dependent regulation of TGFbeta signaling in cancer

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P2860

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads.

http://www.wikidata.org/entity/Q39791091

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

Cooperative inhibition of bone ...... y Smurf1 and inhibitory Smads.

@en

Cooperative inhibition of bone ...... y Smurf1 and inhibitory Smads.

@nl

type

label

Cooperative inhibition of bone ...... y Smurf1 and inhibitory Smads.

@en

Cooperative inhibition of bone ...... y Smurf1 and inhibitory Smads.

@nl

prefLabel

Cooperative inhibition of bone ...... y Smurf1 and inhibitory Smads.

@en

Cooperative inhibition of bone ...... y Smurf1 and inhibitory Smads.

@nl

P1433

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MBC.E02-07-0441

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Molecular Biology of the Cell

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Cooperative inhibition of bone ...... y Smurf1 and inhibitory Smads.

@en

P2093

Gyo Murakami

http://www.w3.org/2001/XMLSchema#string

Kohei Miyazono

http://www.w3.org/2001/XMLSchema#string

Kunio Takaoka

http://www.w3.org/2001/XMLSchema#string

Takeshi Imamura

http://www.w3.org/2001/XMLSchema#string

Tetsuro Watabe

http://www.w3.org/2001/XMLSchema#string

P2860

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

The ubiquitin system

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

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2809-2817

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10.1091/MBC.E02-07-0441

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7

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14

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