GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance.
about
Dominant GDAP1 mutations cause predominantly mild CMT phenotypesCharcot-Marie-Tooth disease and intracellular trafficLack of GDAP1 induces neuronal calcium and mitochondrial defects in a knockout mouse model of charcot-marie-tooth neuropathyAlteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia.Novel roles for actin in mitochondrial fissionCharcot-Marie-Tooth-related gene GDAP1 complements cell cycle delay at G2/M phase in Saccharomyces cerevisiae fis1 gene-defective cellsWhole genome expression profile in neuroblastoma cells exposed to 1-methyl-4-phenylpyridineAxon Transport and Neuropathy: Relevant Perspectives on the Etiopathogenesis of Familial Dysautonomia.Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission.Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcomeDynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age.Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes.Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domainThe Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.Recent advances in the genetics of hereditary axonal sensory-motor neuropathies type 2.Mitochondrial division: molecular machinery and physiological functions.Demyelinating prenatal and infantile developmental neuropathies.Neural and molecular features on Charcot-Marie-Tooth disease plasticity and therapy.Mitochondrial dynamics in neurodegeneration.Disturbed mitochondrial dynamics and neurodegenerative disorders.Peroxisome-mitochondria interplay and disease.Mitochondrial dynamics in neuronal injury, development and plasticity.CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca2+ entry-stimulated respiration.Mitochondrial Fission in Human Diseases.Regulation of Mitochondrial Dynamics by Proteolytic Processing and Protein Turnover.Clinical and mutational spectrum of Japanese patients with Charcot-Marie-Tooth disease caused by GDAP1 variants.
P2860
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P2860
GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
GDAP1 mutations differ in thei ...... ng on the mode of inheritance.
@en
GDAP1 mutations differ in thei ...... ng on the mode of inheritance.
@nl
type
label
GDAP1 mutations differ in thei ...... ng on the mode of inheritance.
@en
GDAP1 mutations differ in thei ...... ng on the mode of inheritance.
@nl
prefLabel
GDAP1 mutations differ in thei ...... ng on the mode of inheritance.
@en
GDAP1 mutations differ in thei ...... ng on the mode of inheritance.
@nl
P2093
P1476
GDAP1 mutations differ in thei ...... ing on the mode of inheritance
@en
P2093
Konstanze Marion Wagner
Marcel Ruegg
Ueli Suter
P304
P356
10.1016/J.NBD.2009.09.011
P50
P577
2009-09-25T00:00:00Z