Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2.
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Highlights on distinctive structural and functional properties of HTLV Tax proteinsTax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signalingHuman T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells.Recombinant human T-cell leukemia virus types 1 and 2 Tax proteins induce high levels of CC-chemokines and downregulate CCR5 in human peripheral blood mononuclear cells.Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax.Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy.The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1).Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein.The importance of ubiquitination and sumoylation on the transforming activity of HTLV Tax-1 and Tax-2.Interplay between the HTLV-2 Tax and APH-2 proteins in the regulation of the AP-1 pathway.Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein.Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast modelDistinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis.Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.Targeting HTLV-1 activation of NFκB in mouse models and ATLL patients.The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators.HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties.Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB.Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax.Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2.Is there a role for ubiquitin or SUMO in human T-cell leukemia virus type 2 Tax-induced NF-κB activation?Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4+ T cells.Stability of the HTLV-1 Antisense-Derived Protein, HBZ, Is Regulated by the E3 Ubiquitin-Protein Ligase, UBR5.HTLV Deregulation of the NF-κB Pathway: An Update on Tax and Antisense Proteins Role.
P2860
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P2860
Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Identification of a novel moti ...... Tax1 protein from HTLV-2 Tax2.
@en
Identification of a novel moti ...... of human T-cell leukemia virus
@nl
type
label
Identification of a novel moti ...... Tax1 protein from HTLV-2 Tax2.
@en
Identification of a novel moti ...... of human T-cell leukemia virus
@nl
prefLabel
Identification of a novel moti ...... Tax1 protein from HTLV-2 Tax2.
@en
Identification of a novel moti ...... of human T-cell leukemia virus
@nl
P2093
P2860
P356
P1433
P1476
Identification of a novel moti ...... Tax1 protein from HTLV-2 Tax2.
@en
P2093
Masahiko Takahashi
Masahiro Fujii
Masaya Higuchi
Masayasu Oie
Toshiyuki Shoji
Yutaka Aoyagi
P2860
P2888
P356
10.1186/1742-4690-6-83
P577
2009-09-17T00:00:00Z
P5875
P6179
1010737764