Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents.
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Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis.Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectinsSulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanaseHeparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis2015 Clinical trials update in sickle cell anemiaP-selectin mediates metastatic progression through binding to sulfatides on tumor cellsTrousseau's syndrome: multiple definitions and multiple mechanismsMicrovesicle-associated tissue factor and Trousseau's syndromeP-selectin is a host receptor for Plasmodium MSP7 ligandsA chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophilsGlycosulfopeptides with O-glycans containing sialylated and polyfucosylated polylactosamine bind with low affinity to P-selectin.Nonanticoagulant heparin inhibits NF-kappaB activation and attenuates myocardial reperfusion injury.Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands.Impact of venous thromboembolism and anticoagulation on cancer and cancer survivalStepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritisAnticoagulant heparan sulfate precursor structures in F9 embryonal carcinoma cells.Heparin oligosaccharides as potential therapeutic agents in senile dementiaEffect of contact time and force on monocyte adhesion to vascular endothelium.P-selectin, carcinoma metastasis and heparin: novel mechanistic connections with therapeutic implications.Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity.Unfractionated heparin: multitargeted therapy for delayed neurological deficits induced by subarachnoid hemorrhage.Role of endothelial heparanase in delayed-type hypersensitivity.The physiologic and therapeutic role of heparin in implantation and placentation.Heparin-protein interactions.Heparan sulfate proteoglycans.Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome.Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells.Selectins facilitate carcinoma metastasis and heparin can prevent them.Heparan sulfate-dependent enhancement of henipavirus infection.Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparinsInhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence.The heparins and cancer: review of clinical trials and biological properties.Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice.RNA Contaminates Glycosaminoglycans Extracted from Cells and Tissues.Analytical cell adhesion chromatography reveals impaired persistence of metastatic cell rolling adhesion to P-selectin.P-selectin deficiency attenuates tumor growth and metastasisHuman synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activityThe glycoprotein Ib-IX-V complex is a platelet counterreceptor for P-selectin.Anti-thrombotics in thrombosis and cancer.Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo
P2860
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P2860
Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Differential interactions of h ...... eparins as therapeutic agents.
@en
Differential interactions of h ...... eparins as therapeutic agents.
@nl
type
label
Differential interactions of h ...... eparins as therapeutic agents.
@en
Differential interactions of h ...... eparins as therapeutic agents.
@nl
prefLabel
Differential interactions of h ...... eparins as therapeutic agents.
@en
Differential interactions of h ...... eparins as therapeutic agents.
@nl
P2093
P2860
P356
P1476
Differential interactions of h ...... eparins as therapeutic agents.
@en
P2093
K Norgard-Sumnicht
P2860
P304
P356
10.1172/JCI1509
P407
P577
1998-02-01T00:00:00Z