Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease - Wikidata - wikimedia - TriplyDB

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

http://www.wikidata.org/entity/Q39809646

about

The Evi5 family in cellular physiology and pathology Role of Rab GTPases in membrane traffic and cell physiology SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes.In vivo cell biology in zebrafish - providing insights into vertebrate development and disease.Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington's disease mice Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity.Structural basis of membrane trafficking by Rab family small G protein.Regulation of G protein-coupled receptor trafficking and signaling by Rab GTPases Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease.Repeat expansion disease: progress and puzzles in disease pathogenesis Rab11 proteins in health and disease.The role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors.Rab11 in disease progression.Emerging nexus between RAB GTPases, autophagy and neurodegeneration.Critical importance of RAB proteins for synaptic function.Rab11 as a modulator of synaptic transmission.Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease.Traffic jams and the complex role of α-Synuclein aggregation in Parkinson disease.Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease.Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease.Molecular insights into cortico-striatal miscommunications in Huntington's disease.Rab GTPases and Membrane Trafficking in Neurodegeneration.The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival.

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P2860

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

http://www.wikidata.org/entity/Q39809646

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

@en

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease.

@nl

type

label

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

@en

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease.

@nl

prefLabel

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

@en

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease.

@nl

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J.NBD.2009.08.003

P1433

Neurobiology of Disease

P1476

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

@en

P2093

Antonio Valencia

http://www.w3.org/2001/XMLSchema#string

Ellen Sapp

http://www.w3.org/2001/XMLSchema#string

Jonathan Alexander

http://www.w3.org/2001/XMLSchema#string

Kathryn Chase

http://www.w3.org/2001/XMLSchema#string

Kimberly B Kegel

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Laryssa A Comer-Tierney

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Marian Difiglia

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Miguel Esteves

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Neil Aronin

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Nicholas Masso

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P2860

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

Rab GDI: a solubilizing and recycling factor for rab9 protein

Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans-golgi network

Rab11 regulates recycling through the pericentriolar recycling endosome

Rab proteins as membrane organizers

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.

The TRAPP complex is a nucleotide exchanger for Ypt1 and Ypt31/32.

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

The hunt for huntingtin function: interaction partners tell many different stories

Excitotoxic neuronal death and the pathogenesis of Huntington's disease

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374-383

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scholarly article

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10.1016/J.NBD.2009.08.003

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2

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36

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2009-08-20T00:00:00Z

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26759703

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19699304

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P921

Huntington disease

P932

2798579

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