A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms.
about
Genome-wide insights into the patterns and determinants of fine-scale population structure in humansAre rare variants responsible for susceptibility to complex diseases?How many diseases does it take to map a gene with SNPs?Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthmaProtein variation in Adh and Adh-related in Drosophila pseudoobscura. Linkage disequilibrium between single nucleotide polymorphisms and protein allelesEstimation of haplotype frequencies, linkage-disequilibrium measures, and combination of haplotype copies in each pool by use of pooled DNA data.Estimating recombination rates from population-genetic data.Forward-time simulation of realistic samples for genome-wide association studiesA simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other.In silico analysis of disease-association mapping strategies using the coalescent process and incorporating ascertainment and selectionCoalescent-based association mapping and fine mapping of complex trait loci.Precision and high-resolution mapping of quantitative trait loci by use of recurrent selection, backcross or intercross schemes.DNA Pooling: a tool for large-scale association studies.Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.Association mapping via regularized regression analysis of single-nucleotide-polymorphism haplotypes in variable-sized sliding windows.Extensive linkage disequilibrium in small human populations in EurasiaMicroRNAs related polymorphisms and genetic susceptibility to esophageal squamous cell carcinoma.An efficient haplotyping method with DNA pools.An isochore transition in the NF1 gene region coincides with a switch in the extent of linkage disequilibrium.A variable-sized sliding-window approach for genetic association studies via principal component analysis.Replication of genetic associations as pseudoreplication due to shared genealogy.Recovering frequencies of known haplotype blocks from single-nucleotide polymorphism allele frequencies.Inflated false-positive rates in Hardy-Weinberg and linkage-equilibrium tests are due to sampling on the basis of rare familial phenotypes in finite populations.A non-threshold region-specific method for detecting rare variants in complex diseases.GENOME: a rapid coalescent-based whole genome simulator
P2860
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P2860
A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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name
A coalescent approach to study ...... ngle-nucleotide polymorphisms.
@en
A coalescent approach to study ...... ngle-nucleotide polymorphisms.
@nl
type
label
A coalescent approach to study ...... ngle-nucleotide polymorphisms.
@en
A coalescent approach to study ...... ngle-nucleotide polymorphisms.
@nl
prefLabel
A coalescent approach to study ...... ngle-nucleotide polymorphisms.
@en
A coalescent approach to study ...... ngle-nucleotide polymorphisms.
@nl
P2860
P356
P1476
A coalescent approach to study ...... ngle-nucleotide polymorphisms.
@en
P2093
von Haeseler A
P2860
P304
P356
10.1086/302766
P407
P577
2000-02-01T00:00:00Z